• 研究氢化活性中心桥结构原子是否起到质子摆渡作用设计了在分子引入氢键的结构。

    To explore the role of the bridged N atom for a possible proton transfer in the active site of hydrogenase, we tried to introduce a hydrogen bond into a couple of designed molecules.

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  • 他们设计一个特殊抑制物(分子),可以结合人类DDAH活性位点上。

    They also designed specific inhibitors (small molecules) which bind to the active site of human DDAH.

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  • 研究进一步理解酰脲类分子结构、药物活性设计新的分子提供了帮助指导

    This study will provide assistance and guidance to further understand molecular structure of sulfonylurea and its herbicidal activity and to design new compounds.

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  • 目的筛选鉴定CD59分子特异结合的短肽,设计具有拮抗CD59肿瘤逃逸活性的短肽封条奠定基础。

    AIM: To screen and identify the short-peptide which specifically bind to human CD59 so as to design short-peptide clamp with counteracting tumor escape activity.

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  • 分子前药设计合成载体活性药物连接基的选择进行了论述。

    The design and synthesis of macromolecular prodrugs, choice of polymer carrier, active drug and linker are introduced.

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  • 研究目的是分子设计构建G-CSF单体分子具有半衰期更长、生物活性更高的新型重组人G-CSF/G-CSF双体分子(简称G-G),并原核系统进行高效表达

    Molecule design, construction and high level expression in E. coli. of bimolecular G-CSF with longer half life and higher bioactivities than single molecular G-CSF.

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  • 聚合物表面活性分子结构设计优化提高复合驱油体系性能的影响还有待研究。

    But how the molecules structure design and optimization of polymer and surfactant would improve the binary oil-displacing system remains to be seen.

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  • 为了寻求一种切实可行及表达活性分子ngf生产途径我们通过基因工程细胞工程技术设计两种NGF的体外重组方案。

    To look for a good method to producing NGF which has low molecular weight, we designed two projects which are carried out through gene cloning and cell engineering techniques to provide the problem.

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  • 设计合成了含有活性基-羧基、氨基羟基尼罗尼罗兰衍生物用来标记生物分子

    Nile red and Nile blue derivatives with carboxyl or amino or hydroxyl group were synthesized, which were used to tag biological molecules.

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  • 设计合成了含有活性基-羧基、氨基羟基尼罗尼罗兰衍生物用来标记生物分子

    Nile red and Nile blue derivatives with carboxyl or amino or hydroxyl group were synthesized, which were used to tag biological molecules.

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