本制粒法可用于水溶性药物控释制剂的制备。
These results suggested that this granulation method was useful in preparing a sustained release preparation of water soluble medicine.
因此，多层骨架片系统是制备高水溶性药物控释制剂的有效方法。
The system of multi-layered matrix tablets provided an effective method for zero-order release of highly soluble drugs.
使用范围：可用于生产中、高档水溶性药物，完全可替代无水葡萄糖和乳糖！
Use scope: may use in the production, the upscale water-soluble medicine, definitely may substitute anhydrous glucose and lactose!
水溶性药物盐酸雷尼替丁极易吸湿变色，其造粒和包衣操作存在一定的难度。
Ranitidine hydrochloride, a water-soluble drug, is easy absorb moisture and produce discoloration.
结论：采用控释薄膜包衣技术和骨架控释技术可用于制备强水溶性药物控释制剂。
CONCLUSION: the controlled release film-coated technique and the matrix technique can be used to prepare controlled release tablets for highly hydrophilic drugs.
然而，使用纳米粒包裹小分子量的水溶性药物，会受药物包囊效率低及包囊药物快速释放差的限制。
However, the use of nanoparticles for small molecular weight, water-soluble drugs has been limited by poor drug encapsulation efficiency and rapid release of the encapsulated drug.
本发明的聚合物主要应用于水溶性药物缓释包衣，添加少许不溶性成份或致孔剂即可达到满意的缓释效果。
The polymer is mainly applied to the water soluble drug sustained release coating, and can reach a satisfied sustained release effect by adding a few insoluble components or pore-forming agents.
水溶性药物的另一个屏障是胶质结缔组织细胞(星形细胞)，该细胞所形成的星形细胞鞘与毛细血管内皮基膜紧密邻接。
Another barrier to water-soluble drugs is the glial connective tissue cells (astrocytes), which form an astrocytic sheath close to the basement membrane of the capillary endothelium.
目的：考察水溶性联合载体在增加难溶性药物的溶出速率上是否优于单一载体，并制备速释型固体分散体。
Objective: to investigate whether the combined carrier is superior to the single carrier in improving dissolution of poorly insoluble water drug and prepare a fast released solid dispersion.
目的：考察水溶性联合载体在增加难溶性药物的溶出速率上是否优于单一载体，并制备速释型固体分散体。
Objective: to investigate whether the combined carrier is superior to the single carrier in improving dissolution of poorly insoluble water drug and prepare a fast released solid dispersion.
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