因为男性只有一条从母亲那里遗传来的X染色体，因此他们的TEX11基因只有一个拷贝，理论上来说，TEX11基因的任何突变都可以导致不育。
Because men have only one X chromosome that they inherit from their mother and thus only one copy of the TEX11 gene, any mutation could theoretically lead to sterility.
几十年来，传统的理论认为X染色体与减数分裂以及男性不育无关，因为在男性减数分裂过程中X染色体被沉默掉了。
For decades, conventional wisdom stated that the X chromosome had little to do with meiosis or infertility because the X chromosome is silenced during male meiosis.
前言：目的：分析研究染色体异常在男性不育中的诊断意义。
Objective: To study the diagnostic significance of chromosome abnormality in male infertility.
结论染色体异常是造成男性不育的重要遗传因素。
Conclusion The chromosomal anomalies are important inheritance factor for male sterility.
染色体平衡易位携带者由于自身染色体是平衡的因此没有异常表型，但将导致不育、流产、死胎、畸胎、胎儿宫内和出生后生长缺陷。
Although the carriers of chromosomal balanced translocation have normal phenotypes they would lead to infertility, abortion of fetus, malformation of fetus and congenital defects after born.
目的探讨不孕不育及自发流产与染色体核型异常的关系，指导临床对这些疾病的诊断。
Objective: To investigate the relationship between sterility, spontaneous abortion and abnormal chromosome karyotypes, and that would be help for clinical diagnose for hereditary disease.
方法：采取132例男性不育患者外周血进行染色体核型分析。
Method:Karyotypes of 132 infertile men were analyzed by chromosome G banding and C banding methods.
方法采取2477例不育男性的外周血进行染色体核型分析。
Methods Karyotypes of 2477 infertile men were analyzed by chromosome G banding and C banding analysis.
目的：探讨非特发性男性不育症与Y染色体微缺失的关系。
Objective:To explore the relationship between Y chromosome microdeletion and non-idiopathic infertility in male cases with dyszoospermia.
结果1009例男性不育患者中染色体异常者有61例，异常率为6.05%，染色体多态性者43(4.26%)例。
Results: There were 61 patients with chromosome abnormalities among 1009 infertility male, the abnormal rate was 6.05%, and 43 (4.26%) patients with chromosome polymorphism.
男性不育原因多样，大量研究表明Y染色体微缺失与男性不育的关系密切。
Male infertility can be induced by many factors, and extensive studies have strongly indicated that Y chromosome microdeletions are closely related to male reproductive dysfunction.
由此表明，该雄性不育系的不育性与染色体结构变异有关。
Therefore, that means the male sterility is related to structure of chromosome change.
目的研究中国人群男性不育患者的染色体异常频率分布。
Objective To investigate the frequency of chromosome abnormality in 415 infertile males.
方法：对近6年于北京大学人民医院不孕不育门诊进行咨询的1624例患者中，存在染色体异常的患者，进行染色体核型及临床分析。
Methods: Among 1624 patients consulted in infertility clinic in our hospital from recent 6 years, chromosome karyotype and clinical analysis were conducted in abnormal chromosome patients.
方法5 0 9例男性不育患者行外周血淋巴细胞G显带染色体核型分析。
Methods: Chromosomal karyotypes were examined in 509 male infertile patients by periphery blood lymphocyte culture and G banding.
方法5 0 9例男性不育患者行外周血淋巴细胞G显带染色体核型分析。
Methods: Chromosomal karyotypes were examined in 509 male infertile patients by periphery blood lymphocyte culture and G banding.
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