• 树突状细胞属于抗原递呈细胞

    Liver-derived dendritic cells belong to the antigen-presenting cells.

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  • 辅助T细胞激发针对病原免疫反应之前,必须感觉到位于抗原递细胞表的入侵者分子片段

    Before a helper t cell can trigger a response to a pathogen or parasite, it has to "feel" these molecular bits of an invader displayed on the surface of an antigen-presenting cell (APC).

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  • 它们位于血管网周围,可以起到抗原递呈细胞作用。抗原递呈细胞启动针对抗原免疫反应并释放入血。

    They are found in a perivascular network and may serve as the antigen presenting cell which initiates immune responses to antigens delivered through the circulation.

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  • 我们知道,人体外来抗原免疫应答依赖t细胞特异性抗原递呈细胞(APC)之间协调相互作用

    It is generally accepted that normal immune response to extrinsic antigens depends on coordinating interaction between t cells and antigen presenting cells (APCs).

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  • 第一信号抗原T细胞受体TCR结合第二信号为抗原递呈细胞的协同刺激分子与T、B淋巴细胞上的受体结合。

    The first signal is the binding of antigen with TCR on T cells. The second signal is the binding of co-stimulate on the APC with their receptors presenting on T and B lymphocytes.

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  • 树突状细胞目前发现抗原功能最强的专职抗原递呈细胞也是唯一能够激活初始免疫应答的APC,在对肿瘤产生主动免疫重要作用

    Dendritic cells is a function of the recursive antigen found most full-time antigen oral cells, also can activate the immune response, the initial APC on immunization tumors plays an important role.

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  • 结论肿瘤免疫治疗中,脉冲致敏DC一定要灭活肿瘤细胞作为抗原刺激物,才能有效地完成抗原递呈功能

    Conclusion: DC with pulse sensitization should use deactivated tumor cells as antigen stimulator substance, then, effectively perform antigen-presenting function in immune treatment of antitumor.

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  • 肥大细胞具有识别吞噬并杀灭病原微生物的功能外,尚加工、抗原调节免疫反应

    Mast cells not only have the ability to recognize and phagocytize pathogens, then kill them, but they can also present antigens and regulate immunity response.

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  • 目的:探讨改善外周血来源树突状细胞DC体外培养方法促进DC成熟提高递呈抗原激发特异性免疫反应的能力。

    PART I The Improvement of Dendritic Cell Culture Measures in vitroObjective: Improve the measures of dendritic cell culture in vitro, to increase the rate of mature and function of DC.

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  • 结果NS1骨髓瘤细胞同一孔池培养DC数目减少形态改变抗原递呈功能下降

    Results: the number of DC which were cultured in the same Wells with NS1 tend to decrease, the cellular appearance changed and the ability of presenting antigen decreased.

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  • 病毒干扰宿主免疫细胞对病毒抗原摄取递呈杀伤等方面阐述病毒抗感染免疫应答研究进展

    The research advances were reviewed on the aspects of virus's interfering with immunocyte intaking, presenting and killing antigen of the virus.

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  • 淋巴细胞识别主要组织相容性复合物(MHCIII分子递呈抗原片段

    T lymphocytes recognize antigenic peptide fragments presented by major histocompatibility complex(MHC) class I or class II molecules.

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  • 捕获肿瘤抗原后,DC迁移TDLN,发育成熟递呈抗原,诱导T细胞分化成熟杀伤肿瘤细胞

    After capturing tumor antigen, DC migrates to TDLN where it becomes matured and starts presenting antigen, then induces t cell differentiation, maturation and to kill tumor cells.

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  • 糖尿病肾病患者外周血单核细胞DC分化能力显著低于正常人,分化成的DC递呈抗原,但亚比例失调

    Hemodialysis could ameliorate the differentiation of Monocytes into Dendritic cells and antigen presenting capacities, while the proportion of DC subsets disorder.

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  • 因此树突状细胞(DC细胞)递呈肿瘤抗原培养CIK细胞希望可以增强CIK细胞识别肿瘤的能力以及提高肿瘤杀伤活性。

    Hence, dendritic cells (DC) were cultured and engineered to present tumor antigens to CIK cells hoping that this might enhance the recognition of tumor cells and its subsequent killing.

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  • 树状细胞(DC)具有强大抗原递呈能力,并有效激发T细胞应答,是目前肿瘤免疫治疗研究的热点之一。

    It has been proved that Dendritic cells (DCs) have strongly ability to present antigen. DCs can trigger t cell responses and enhance the t cell mediated anti tumor effect.

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  • 结论失血合并闭合性骨折导致小鼠dth反应低下,与创伤后DC引流淋巴结内细胞递呈抗原能力显著下降密切相关。

    Conclusion Hemorrhage combined with closed fracture decreases the DTH responses in mice, which may be attributed to the reduced antigen-presenting capacity of DC in the injured mice.

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  • 结论失血合并闭合性骨折导致小鼠dth反应低下,与创伤后DC引流淋巴结内细胞递呈抗原能力显著下降密切相关。

    Conclusion Hemorrhage combined with closed fracture decreases the DTH responses in mice, which may be attributed to the reduced antigen-presenting capacity of DC in the injured mice.

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