目的探讨体外循环(CPB)期间低温改良低钾右旋糖酐(LPD)溶液肺动脉灌注对CPB中肺血管内皮细胞损伤的保护作用。
Objective To test the effect of pulmonary artery perfusion with modified low-potassium dextran (LPD) solution on lung vascular endothelial cell injury during cardiopulmonary bypass (CPB).
以循环内皮细胞(CEC)作为血管内皮损伤的指示物，血浆内皮素(ET - 1)反映血管内皮的功能变化。
Circulating endothelial cells (CEC) were used as an endothelial injury indicator and the plasma level of endothelin (ET-1) as the functional marker of the vascular endothelial cells.
目的：探讨改善微循环对周围神经嵌压性损害血管内皮细胞生长因子(VEGF)表达和病理改变的影响。
Aim: to study the influences on expression of vascular endothelium growth factor (VEGF) and pathologic changes by improving microcirculation following crushing lesion of sciatic nerve in rats.
血管内皮祖细胞是一类能循环、增殖并能直接分化为血管内皮细胞的前体细胞。
Endothelial progenitor cell (EPC) is a subtype of progenitor cells that can circulate, proliferate and have the ability to differentiate into mature endothelial cells.
结论NAC可以抑制CPB血清所致的培养血管内皮细胞ICAM - 1表达增加。因此NAC对体外循环后全身炎症反应可能有保护作用。
Conclusion NAC could inhibit ICAM-1 expression on cultured endothelial cells, and might play a role in attenuating systemic inflammatory response syndrome induced by CPB.
结论NAC可以抑制CPB血清所致的培养血管内皮细胞ICAM - 1表达增加。因此NAC对体外循环后全身炎症反应可能有保护作用。
Conclusion NAC could inhibit ICAM-1 expression on cultured endothelial cells, and might play a role in attenuating systemic inflammatory response syndrome induced by CPB.
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