目的总结帕米膦酸钠在成骨不全症中的应用经验。
Objective To summarize the experience of pamidronate for osteogenesis imperfecta.
结论帕米膦酸钠对成骨不全症有较好疗效，但需更多病例观察。
Conclusion Pamidronate therapy has a positive effect on patients with osteogenesis imperfecta, while this still remains to be demonstrated in more patients with osteogenesis imperfecta.
结果两例对帕米膦酸钠有较好耐受性，治疗随访期间未再发骨折。
Results No fracture and significant adverse reaction were seen during pamidronate therapy.
他说，对于那些严重的骨质疏松患者来说，在婴儿期或青春成长末期不要使用静脉注射药物帕米膦酸钠。
He said that those with more severe OI, babies or adolescents at the end of their period of growth, would be better off using the intravenous drug pamidronate.
目的：研究帕米膦酸钠对聚乙烯微粒刺激破骨细胞功能的影响，间接探讨帕米膦酸钠防治人工关节无菌性松动的可能性。
Objective: To investigate the effects of pamidronate on the osteoclasts activated by the polyethylene particles and explore the preventing effect of pamidronate on the aseptic loosening of prosthesis.
目的：研究帕米膦酸钠对聚乙烯微粒刺激破骨细胞功能的影响，间接探讨帕米膦酸钠防治人工关节无菌性松动的可能性。
Objective: To investigate the effects of pamidronate on the osteoclasts activated by the polyethylene particles and explore the preventing effect of pamidronate on the aseptic loosening of prosthesis.
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