以苯甲酰氯为原料,经酰化,还原,环合等反应合成左旋西替利嗪盐酸盐,反应总收率为8.05%。
Levocetirizine Dihydrochloride was prepared from benzoyl chloride by acidylation, hydrogenation, cyclization with an overall yield of 8.05%.
以苯甲酰氯为原料,经酰化,还原,环合等反应合成左旋西替利嗪盐酸盐,反应总收率为8。05%。
Levocetirizine dihydrochloride was prepared from benzoyl chloride by acids lation hydrogenation cyclization with an overall yield of8.05%.
论文通过三条路线,经化学拆分法或手性诱导合成法,对左旋西替利嗪及其中间体的合成进行了研究。
Three synthetic routes to prepare levocetirizine and its intermediates through chemical resolution and chiral induction were studied in the paper.
论文通过三条路线,经化学拆分法或手性诱导合成法,对左旋西替利嗪及其中间体的合成进行了研究。
Three synthetic routes to prepare levocetirizine and its intermediates through chemical resolution and chiral induction were studied in the paper.
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