这些数据集的异常频率能够被计算，并且数据能够在带有基因注释的人类基因组图谱中可视化。
Aberration frequencies can be calculated for these datasets, and the data can be visualized on the human genome map with gene annotations.
在基因组坐标位置下放置有注释的通道，允许快速可视化不同类型信息间的相关性。
It places annotation tracks beneath genome coordinate positions, allowing rapid visual correlation of different types of information.
每个人在单个有注释的基因中，大约携带250到300个丧失功能的变异，以及50到100个涉及遗传性乱序的变异。
Each person is found to carry approximately 250 to 300 loss-of-function variants in annotated genes and 50 to 100 variants previously implicated in inherited disorders.
人类基因组项目完成的一个根本目的是对所有预测的基因及其蛋白产物的辨识与功能注释。
A crucial aim upon the completion of the human genome is the verification and functional annotation of all predicted genes and their protein products.
标准的探针集注释是以基因为中心，也就是将探针集与特定的基因关联起来，而且探针集的表达谱最终会被翻译成基因表达谱。
Standard Affymetrix probe set annotation is gene-centered, i. e. probe set is precisely linked to gene, and probe set expression is interpreted as gene expression.
为了找出编码蛋白质的基因，注释流程结合了“从头开始的基因预测方法”和“与已知基因相似性比较”这两种方法。
To find unknown protein-coding genes, annotation pipelines use a combination of ab initio gene prediction and similarity to experimentally confirmed genes or proteins.
植物基因组序列的注释能够被分成结构注释和功能注释。
Annotation of plant genomic sequences can be separated into structural and functional annotation.
在已经有注释的4 732个基因中，861个基因的编码区中有ssr。
Among 4 732 annotated genes up to now, SSRs were found in 861 genes.
本文综合讨论了目前基因组中基因功能注释存在的问题及解决这些问题的策略与方法。
In this paper, drawbacks in the annotation of gene function currently used in genomics and some strategies beneficial to the annotation of gene function are discussed.
结构注释是所有基因组学的基础，因为没有准确的基因模型，跨分类群理解基因功能或基因进化可能是受阻碍的。
Structural annotation is the foundation of all genomics as without accurate gene models understanding gene function or evolution of genes across taxa can be impeded.
为了识别、定量和注释所有的人类蛋白质编码基因，HPP将使用三种工具：质谱、亲和抗体、以及生物信息学。
To identify, quantify and annotate all human protein-coding genes, the HPP will use three tools: mass spectrometry, antibody affinity and bioinformatics.
用户能够通过来自一幅图上的每个基因的重要的功能快速地扫描，然后当他们发现感兴趣的注释时进入详细的页面。
The users can quickly scan through important functions of each gene from a graph, and then go to detailed pages when they find interesting annotations.
功能注释高度依赖于与其他已知基因或蛋白质的序列相似性，因为在一个基因组规模上的大多数最初的“首过”功能注释是可传递的。
Functional annotation is highly dependent on sequence similarity to other known genes or proteins as the majority of initial "first-pass" functional annotation on a genomic scale is transitive.
结果：这篇文章介绍了一个新的软件套件，对BED和GFF格式的基因组特征的比较，处理和注释。
RESULTS: This article introduces a new software suite for the comparison, manipulation, and annotation of genomic features in BED and GFF format.
随着越来越多的植物基因组序列数据可用，比较注释的价值将会增加。
With the increasing availability of plant genome sequence data, the value of comparative annotation will increase.
这是一个开放性果蝇基因组计划的产物，主要是可以图形化浏览果蝇基因组注释结果。
Apollo is a collaborative open source project between the berkeley drosophila genome project the sanger institute and the ebi.
平行的视图水平的显示了两个基因组注释，通过一个面板显示梯形的局部比对。
The parallel view displays two genome annotations horizontally, synchronized through a panel displaying local alignments as trapezoids.
以一种比较方式进行跨基因组的联合结构注释和功能注释促进了更准确的注释以及对基因和基因组进化的一个理解。
Coupling structural and functional annotation across genomes in a comparative manner promotes more accurate annotation as well as an understanding of gene and genome evolution.
背景：目前，大部分基因组注释是由具有有限资源的集中的小组所策划。
BACKGROUND: Currently, most genome annotation is curated by centralized groups with limited resources.
该工具特别高效，并允许用户用公开的和定制的基因组注释轨道比较大的数据集(例如，下一代测序数据)。
The tools are extremely efficient and allow the user to compare large datasets (e. g., next-generation sequencing data) with both public and custom genome annotation tracks.
因此它被广泛地用作序列描述与注释、系统发生、基因组学、转录组学和蛋白质组学研究的一个起始步骤。
It is thus widely used as an initial step for sequence characterization and annotation, phylogeny, genomics, transcriptomics, and proteomics studies.
搜索结果通常被用于各种功能基因组学和比较基因组学任务，例如注释未知序列，研究基因模型和比较两个序列集合。
The search results are commonly adopted for various functional and comparative genomics tasks such as annotating unknown sequences, investigating gene models and comparing two sequence sets.
MGD是小鼠基因、等位基因和品种系统命名法及小鼠基因的表型和功能注释的权威来源。
MGD is the authoritative source for mouse gene, allele and strain nomenclature and for phenotype and functional annotations of mouse genes.
结构注释依赖于敏感的、特异的计算程序和深刻的实验证据来识别基因组DNA中的基因特征。
Structural annotation is dependent on sensitive, specific computational programs and deep experimental evidence to identify gene features within genomic DNA.
它以充当包含病毒完整基因组序列、增值的推断数据和数据挖掘工具的一个注释和精选数据库为目的而开发。
It has been developed with the objective of serving as an annotated and curated database comprising complete genome sequences of viruses, value-added derived data and data mining tools.
最初是为了注释人类基因组而创建的，特征丰富的UCSC基因组浏览器可以被应用到任何测序的物种。
The feature-rich UCSC Genome Browser, created originally to annotate the human genome, can be applied to any sequenced organism.
最初是为了注释人类基因组而创建的，特征丰富的UCSC基因组浏览器可以被应用到任何测序的物种。
The feature-rich UCSC Genome Browser, created originally to annotate the human genome, can be applied to any sequenced organism.
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