在促炎症反应如内毒素、缺血再灌注损伤和免疫反应中,过量释放的细胞因子和前列腺素样物质可引起肝损伤。
During proinflammatory reactions such as endotoxemia, ischemia - reperfusion and immune reactions, excessive amounts of cytokines and prostanoids are released resulting in liver injury.
不过,酪氨酸激酶是直接参与还是通过前列腺素和一氧化氮合酶对糖尿病炎症产生反应的,我们目前还不知道。
However, the involvement of tyrosine kinase either directly or through the prostaglandins and nitric oxide synthase in response to inflammation during diabetes is not completely understood.
对血压、凝血能力、疼痛知觉和生殖机制有重要作用,但一种特定的前列腺素,在不同的组织中可以产生不同的甚至相反的效果。
They have important effects on blood pressure, blood clotting, pain sensation, and reproduction mechanisms, but one prostaglandin may have different and even opposite effects in different tissues.
前列腺素和白三烯是重要的免疫功能,平滑肌功能,血小板聚集和炎症。
Prostaglandins and leukotrienes are important in immune function, smooth muscle function, platelet aggregation and inflammation.
前列腺素对身体有很多影响。一部分能引起疼痛和和受损组织的扩张。另一部分就是保护胃壁和肠道壁。
Prostaglandins have several effects on the body. Some cause pain and the expansion, or swelling, of damaged tissue. Others protect the lining of the stomach and small intestine.
前列腺素也可以造成心脏,肾和血液工作的更好。但是存在一个问题。阿司匹林会阻止所有前列腺素的运转,好的和坏的。
Prostaglandins also make the heart, kidneys and blood vessels work well. But there is a problem. Aspirin works against all prostaglandins, good and bad.
目前来看,它的作用是上调前列腺素e2(一种帮助头发生长的激素),同时能够抑制雄激素受体的相关功能,促进和保护了头发毛囊的生长。
Basically what it does is up-regulate PGE2 which AIDS in hair growth, suppresses androgen receptor related functions, promotes maintenance, and significantly improves the functions of hair follicles.
阿司匹林:乙醯水杨酸的俗称,1899年发现的一种有机化合物。系水杨酸和醋酸的酯,会抑制前列腺素的生成。
Aspirin: Common name of acetylsalicylic acid, an organic compound introduced in 1899. The ester of salicylic acid and acetic acid, it inhibits production of prostaglandins in the body.
通过化学反应和柱层析,AA转变为PGG_2和PGH_2的转换率大约为34%,前列腺素内过氧化物的纯度可达90%以上。
The conversion rate from AA into PGG2 and PGH2 by chemical reaction and column chromatography was about 34%. The purity of endoperoxide products was more than 90%.
前列腺素e_1对炎症效应细胞的抑制作用和对肺细胞的保护作用有显著的剂量-效应关系。
There are significant dose-response relationships for the inhibitory effect of PGE_1on inflammatory effector cells and the cytoprotective effect of PGE_1 on lung cells.
应用漂浮导管监测前列腺素E1(PGE1)对11例以二尖瓣狭窄为主的风湿性心脏病合并肺动脉高压患者的体循环和肺循环的血液动力学作用。
The hemodynamic effects of prostaglandin E1(PGE1)on pulmonary and systemic circulations were studied in 11 patients with rheumatic mitral disease complicated by pulmonary hypertension.
目的系统评价前列腺素e1治疗慢性肾功能衰竭的疗效和安全性,为临床选用前列腺素e1治疗该病提供循证药学证据。
Objective to determine the effectiveness and safety of PGE1 in patients with chronic renal failure (CRF) and to provide the proof of evidence-based pharmacy.
一种可能的选择是米索前列醇的标示外使用,这是一种合成的前列腺素E1类似物,被核准用于防止和治疗胃肠道溃疡。
One possible option in this setting is the off-label use of misoprostol, a synthetic prostaglandin E1 analogue licensed for prevention and treatment of gastrointestinal ulcers.
本文主要以前列腺素受体为分类依据,综述各类受体的特性以及相关药物的临床应用和研究进展。
This review summarizes the properties of each type of prostaglandin receptor, and the clinical applications and research progress of drugs targeting their corresponding prostaglandin receptors.
本文主要以前列腺素受体为分类依据,综述各类受体的特性以及相关药物的临床应用和研究进展。
This review summarizes the properties of each type of prostaglandin receptor, and the clinical applications and research progress of drugs targeting their corresponding prostaglandin receptors.
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