目的探讨吲哚美辛中间体精制条件。
Objective To discuss the purification condition of Indomethacin intermediate.
应用钾、吲哚美辛、GH治疗是有效的。
Treatment with potassium, indomethacin, and GH has been effective.
目的以热熔挤出技术制备吲哚美辛速释胶囊。
Objective To prepare indomethacin immediate release capsules by means of hot-melt extrusion (HME) using indomethacin as the model drug.
目的探讨吲哚美辛搽剂的制备及质量控制标准。
Objective To study the preparation process and quality control method of indomethacin liniment.
现有的研究仅在增加骨筋膜室压力前给予吲哚美辛。
Existing studies have only considered indomethacin administration before induction of elevated intracompartment pressure.
目的：制备吲哚美辛肠溶包衣微丸，考察其释放特性。
OBJECTIVES: To prepare indomethacin enteric coated pellets and investigate their release properties.
方法湿法制粒压片法制备吲哚美辛果胶氯化钙骨架片。
METHODS Wet granulation technique was employed to prepare pectin-calcium chloride matrix tablets.
目的：制备吲哚美辛肠溶包衣徽丸，考察其释放特性。
OBJECTIVES: To prepare indomethacin enteric-coated pellets and investigate their release properties.
效果以联合用药组最好，姜黄素组次之，吲哚美辛组稍差。
The best result is in the combination group, followed by the curcumin group, indole group of somewhat less.
结论吲哚美辛通过多因素协同作用对小鼠具有较强抗着床作用。
Conclusion Indomethacin can effectively inhibit the implantation through the synergistic action of multiple factors.
于不同时间点取血，以反相高效液相色谱法测定吲哚美辛的血药浓度。
Then we collect the blood in different time point and assay the blood concentration of indomethacin by RP-HPLC.
制备了吲哚美辛肠溶分散片，考察辅料对其崩解时限及溶出速度的影响。
Indomethacin enteric dispersible tablets were prepared, and factors affected disintegration time and dissolution rate were studied.
目的探讨吲哚美辛在海水浸泡火器伤伤口局部应用对浸泡组织活力的影响。
Objective to study the effect of focally applied indomethacin to firearm wound after seawater immersion on viability of the tissue.
吲哚美辛的作用是部分时间依赖性的，无论何时给药都能提高一些组织活力。
The benefits of indomethacin were partially time-dependent; some improvement in tissue viability occurred regardless of timing of administration.
结果：总有效率吡罗昔康组为90％，吲哚美辛组为77％（P＜0．05）。
RESULTS: The total effective rates were 90% for Pir and 77% for Ind (P<0.05).
结论吲哚美辛应用于浸泡火器伤伤口能在浸泡后24小时内抑制伤口过度炎症反应，减轻继发损伤。
Conclusion Indomethacin focally applied to firearm wound during 24 hours after seawater immersion inhibits hyperinflammation and decrease secondary injury.
近年来的研究和临床实践发现吲哚美辛还可用于痛经症状的缓解、手术后疼痛和肿瘤止痛的阶梯治疗。
In recent years clinical studies indicated that indomethacin had therapeutical effect on dysmenorrhea, the pains of operation, acesodyne of tumor.
方法采用吲哚美辛、幽门结扎法制作大鼠急性胃溃疡模型，观察并比较黄芪与雷尼替丁抗胃溃疡的效果。
Methods By establishing acute gastric ulcer model in mice, the different preventive roles of Milkrentch root and ranitidine were observed and compared.
目的：研究泛素蛋白质酶途径在癌性恶病质小鼠骨骼肌中的表达以及吲哚美辛(IND)对其的调控作用。
Objective: To investigate the expression of ubiquitin-proteasome pathway in skeletal muscle of cachectic mice and the effect of indomethacin (ind) on it.
基于该点考虑，本研究将采用壳聚糖、海藻酸钠、氯化钙、卡波普等为辅料制备吲哚美辛生物粘附凝胶小球。
In order to eliminite bad effect of Indomethacin, Chitosan, Sodium Alginic Acid, Calcium chloride and Carbopol were adopted as additives to make bioadhesive gel beads.
方法：采用盐酸乙醇、氢氧化钠、吲哚美辛致大鼠急性胃黏膜损伤模型、小鼠番泻叶致泻模型和家鸽呕吐模型。
Objective:To study the effects of Huanglian Houpu pill (HLHP) on the acute gastric mucosal damage, diarrhea and vomiting models in animals.
目的：研究吲哚美辛的无保护流体室温燐光（NP-RTP）性质，建立NP-RTP测定吲哚美辛含量的方法。
To study the non-protected fluid room temperature phosphorescence (NP-RTP) proper- ties of indometacin and establish a determination of indometacin by NP-RTP.
将上述指标进一步采用LSD的方法进行两两比较，比较结果以联合用药组最佳，姜黄素组居中，吲哚美辛组较差。
Further use of the above indicators LSD pairwise comparison methods to compare results to the combination group the best, the curcumin group center, indole group of poor.
采用热板法，分别测定小鼠在各时间点注射生理盐水、NS- 398、SC - 560或吲哚美辛后的疼痛阈值。
By exploring hot plate test, we observed the reacting time of animals after injection of saline, NS-398, SC-560 and indomethacin at different time points.
结果低浓度的吲哚美辛即可引起RGM-1细胞受损并且呈量效关系，LPS可以明显减轻这一作用（P<0.05）；
Results The result of LDH leakage showed that indomethacin could induce the injury of RGM-1 in a dose dependent manner and LPS could lessen it significantly (P<0.05).
采用热板法，分别测定小鼠在各时间点注射生理盐水、NS- 398、SC - 560或吲哚美辛后的疼痛阈值。
By exploring hot plate test, we observed the reacting time of animals after injection of saline, NS-398, SC-560 and ind.
对于那些研究吲哚美辛在阿尔茨海默氏症患者治疗中用途的医生，他的研究结果可帮助他们理解他们在临床实践所看到的现象。
His findings help to explain what doctors who are studying the use of indomethacin to treat people with Alzheimer's disease are seeing in their clinical practice.
对于那些研究吲哚美辛在阿尔茨海默氏症患者治疗中用途的医生，他的研究结果可帮助他们理解他们在临床实践所看到的现象。
His findings help to explain what doctors who are studying the use of indomethacin to treat people with Alzheimer's disease are seeing in their clinical practice.
应用推荐