卡马西平—糖精共晶体的溶解度是根据溶解度原理通过静态方法确定的。
The solubility of carbamazepine-saccharin cocrystal was determined by a static method basing on the principle of solubility product.
卡马西平和阿莫西林能同时吃么？
目的探讨卡马西平治疗癫痫的临床疗效。
Objective To explore the clinical effects of carbamazepine used in treatment of epileptic patients.
认为卡马西平是一种安全、可靠的抗躁狂药物。
Accordingly, carbamazepine is considered as a reliable antimanic measure.
TPM对卡马西平及丙戊酸钠血药浓度影响不大。
The effects of the blood concentration weren't great on TPM to carbamazepine and valproate.
目的考察中国癫痫患者卡马西平的群体药动学参数。
AIM To investigate the pharmacokinetic profile of carbamazepine (CBZ) in Chinese epilepsy patients.
结果对部分型癫痫单用卡马西平有效率72.2%。
Results The effective rate of using carbamazepine in partial seizure epilepsy alone is 72.2%.
儿童和青少年患者常使用锂盐治疗，但也使用丙戌酸钠和卡马西平。
Children and adolescents with bipolar disorder generally are treated with lithium, but valproate and carbamazepine also are used.
目的：建立卡马西平(CBZ)诱导的骨髓抑制大鼠模型。
Aim: To establish the model of rat bone marrow inhibition induced by carbamazepine tablets (CBZ).
目的：研究复康片预防卡马西平(CBZ)肝毒性的效果。
Aim: to study the preventive effect of Fukang tablet on liver toxicity induced by carbamazepine (CBZ).
目的：研究长期服用卡马西平对大鼠小脑结构及功能的影响。
Objective: To study the effect of long-term administration of CBZ on the structure and function of rats' cerebellum.
结论复康片可预防或拮抗卡马西平对大鼠骨髓造血功能的抑制。
Conclusion FT can prevent or antagonize the inhibition of hematopoiesis of rat bone marrow induced by CBZ.
背景：卡马西平是部分性癫痫发作的首选药，这点已被普遍接受。
BACKGROUND: Carbamazepine is widely accepted as a drug of first choice for patients with partial onset seizures.
方法采用大鼠在体肠灌流方法，研究卡马西平大鼠肠吸收动力学。
Methods The absorption kinetics and absorption sites were investigated by using in situ perfusion method in rats.
目的评价国产卡马西平(CBZ)在治疗躁狂发作中的临床实用性。
Objective The purpose of this study was to evaluate clinical practicality of carbamazepine (CBZ) made in our country in treatment of manic episode.
暴露在丙戊酸钠下具有比其他抗癫痫药更高的出生缺陷，比如卡马西平和拉莫三秦。
That valproate exposure carries a higher risk of birth defectsthan other antiepileptics, such as lamotrigine and carbamazepine, is not new knowledge, Torbjorn Tomson, M.D.
丙戊酸钠和卡马西平是强有力的肝酶诱导剂，使丙戊酸钠血浓度降低。
PTH and CBZ are potent inducers of hepatic enzyme and can lower the serum concentration of VPA.
卡马西平在志愿者近端小肠定点释放后吸收速率缓慢，吸收总量较好。
The pharmacokinetics of Carbamzepine showed that there were slow and good absorption in upper small intestine of healthy volunteers.
目的观察中药复康片不同时间给药对卡马西平所致大鼠小脑毒性的影响。
Objective To observe the different prevention effect of TCM on the damnification of cerebellum induced by Carmaciping (CBZ) if Fukang tablets were given in different time.
结论：应用HPLC法对卡马西平进行TDM，可以用手指血代替静脉血。
CONCLUSIONS: The finger prick blood can be used for TDM of CBZ by HPLC instead of venous blood.
目的：评价丙戊酸钠与卡马西平对锂盐治疗无效的躁狂发作的疗效和副反应。
Objective: to evaluate the efficacy and side effects of sodium valproate and carbamazepine in the treatment of manic episodes refractory to lithium carbonate.
方法对78例癫痫患者采用卡马西平治疗方案，检测患者血药浓度，分析治疗效果。
Methods 78 cases of epileptic patients were treated with carbamazepine and the blood concentration were detected, too, then the clinical effect were analyzed.
目的探讨利用手指血取样代替静脉血对卡马西平进行TDM(治疗药物监测)的可能性。
Objective Explore the possibility of finger-prick blood being monitored for therapeutic drug monitoring (TDM) of carbamazepine (CBZ) instead of venous blood.
卡马西平处理可以使HSP90乙酰化水平升高，并且破坏HSP90的分子伴侣功能。
Cabamazepine treatment could induce a higher acetylation level of HSP90 and destroy its chaperon function.
目的研究家兔灌服柚汁后对卡马西平血药浓度及药代动力学的影响，为临床合理用药提供参考。
Objective To study the influence of grapefruit juice on the pharmacokinetics of carbamazepine in rabbits so as to provide reference for rational administration in clinical practice.
目的探讨卡马西平睡前一次用药治疗常染色体显性遗传夜间额叶癫(adnfle)患儿的疗效及其与生物节律的关系。
Objective to study the effect of autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) with carbamazepine being taken at a draught before sleep and its relationship with biological rhythm.
目的建立反相高效液相色谱（HPLC）法，以安定为内标，同时测定血清中卡马西平（CBZ）和地尔硫（DZ）的浓度。
Objective To establish reversed phase HPLC method for simultaneous determination of the concentration of carbamazepine(CBZ)and diltiazem(DZ) in serum, using diazepam as internal standard.
结果洋金花对大鼠后放发作行为的发作级数有明显减轻作用（P<0.05），但减轻程度比卡马西平组弱（P<0.01）。
Results Datarametel L relieved the progression of after-discharge seizure behavior in experiment rats significantly(P<0.05)The effects was weaker than that of carbamazepine(P<0.01).
研究人员在科学杂志在线版称，该发现为卡马西平（得理多）立即在相应患者中进行临床试验奠定了基础，尤其是该药的安全性众所周知。
The findings form a basis for immediate clinical trials of the drug in affected people, especially since the safety profile of the drug is well known, the researchers said online in Science.
方法：采用荧光偏振免疫法对2 6例服用苯妥英钠、74例服用卡马西平、14 4例服用丙戊酸钠的患者血药浓度监测结果及临床疗效分析、评价。
Method: The serum concentration of oral phenytoin, carbamazepine and valproic acid were determined in 26,74 and 144 epileptic patients by fluorescence polarization immunoassay, respectively.
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