内皮素受体拮抗剂,已知对健康有益,但具体机制不明确。
Endothelin receptor antagonists are known to have health benefit but precisely why was an unknown, said Pollock, corresponding author on the study.
目前已知一类称为内皮素受体A拮抗剂的药物能减少蛋白尿。
It's also known that a new class of drugs called endothelin a receptor antagonists reduce protein in the urine.
内皮素受体拮抗剂波生坦是治疗肺动脉高压的有效药物之一。
The endothelin receptor antagonist bosentan is one of the effective drugs for pulmonary arterial hypertension.
目的:探讨烧伤血清对心脏微血管内皮细胞内皮素受体的影响。
Objective: To investigate the effect of burned serum on the endothelin(ET) receptor in cardiac microvascular endothelial cells(CMEC).
目的:研究不同剂量内皮素受体A拮抗剂FR139317对大鼠心力衰竭模型的作用。
AIM: To study the effects of a selective endothelin receptor A (ETA) antagonist FR139317 on rats with congestive heart failure.
探讨内皮素受体(etr)亚型基因表达在门静脉高压症胃病(PHG)中的变化及作用。
To study the role of the gene expression of ET-1 receptor (ETR) in the development of portal hypertensive gastropathy (PHG).
结论内皮素受体拮抗剂BQ - 123对缺血性急性肾功能衰竭早期之肾脏具有一定的保护作用。
Conclusion the endothelin receptor antagonist BQ 123 does provide a certain degree of protection for kidneys from the early stage of IARF.
内皮素是目前已知的缩血管活性最强的生物活性肽之一,通过与内皮素受体结合发挥广泛的生物学活性。
Endothelin is one of the most potent vasoconstriction peptides, and it plays important physiological role by interacting with its receptors.
本文讨论了实验性蛛网膜下腔出血动物模型的制作方法,内皮素受体在蛛网膜下腔出血诱发脑血管痉挛中的作用。
The author also discussed the methods of the animal model of the subarachnoid hemorrhage and the effect of endothelin receptor on the cerebral vasospasm caused by subarachnoid hemorrhage.
目的研究中国湖北汉族人群内皮素受体- B (EDNRB)基因的多态性与散发性先天性巨结肠症发病的关系。
Objective To analyze the relationship between polymorphisms of EDNRB gene and Hubei provincial patients of Han ethnicity with sporadic Hirschsprung disease (sHD).
瑞士最大的生物科技公司Actelion股价下跌8.6%,此前该公司生产的内皮素受体拮抗剂克拉生坦没有达到研发的主要目标。
Actelion Ltd., the largest Swiss biotechnology company, sank 8.6 percent after its clazosentan medicine didn’t meet the main goal of a study.
西他生坦服用者中出现不可逆转的肝功能衰竭及其在全球市场的召回事件,强调了对服用内皮素受体拮抗剂的患者进行肝功能监测的重要性。
The irreversible liver failure caused by sitaxsentan and its withdrawal from global markets emphasise the importance of hepatic monitoring in patients treated with endothelin receptor antagonists.
目的观察纳洛酮对内毒素刺激的大鼠离体支气管平滑肌细胞内皮素1和内皮素A受体基因表达的影响。
Objective To investigate the effect of naloxone on the expression of ET 1 and ET AR mRNA in cultured rat bronchial smooth muscle cells stimulated by LPS.
目的探讨运动训练对大鼠心肌组织内皮素- 1 (et - 1)含量、ET受体分型及受体特征的影响。
Objective to explore the effects of sports training on endothelin-1 (ET-1) and endothelin-1 receptor (ETR) and its subtypes in the myocardium in rats.
内皮素(et)是一种血管收缩肽,与et受体结合而发挥作用。
Endothelin (ET) is a recently discovered potent vasoconstrictor peptide exerting effects through combination with its receptor.
目的:探讨内皮素- 1 (et - 1)、内皮素a受体(ETAR)在芥子气中毒病理生理过程中的作用和地位。
AIM: to investigate the role of endothelin-1 (ET-1), endothelin a receptor (ETAR) in pathophysiology of the lung after mustard intoxication.
目的:探讨内皮素- 1 (et - 1)、内皮素a受体(ETAR)在芥子气中毒病理生理过程中的作用和地位。
AIM: to investigate the role of endothelin-1 (ET-1), endothelin a receptor (ETAR) in pathophysiology of the lung after mustard intoxication.
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