目的考察聚乙二醇(PEG)修饰对溶菌酶和粒细胞集落刺激因子(G CSF)活性的影响。
PurposeTo investigate the influence of polyethylene glycol (PEG) modification on the activity of lysozyme and granulocyte colony-stimulating factor (G-CSF).
目的：研究T细胞在巨噬细胞游走抑制因子(MIF)基因修饰的瘤苗诱导抗肿瘤免疫反应中的作用。
Objective: To investigate the role of t cell in the antitumor immune responses induced by MIF gene modified tumor vaccine.
这些修饰为改变染色质结构和易接近性服务，并作为转录因子或其他组蛋白修饰酶的停靠位点。
These modifications serve to alter chromatin structure and accessibility, and to act as docking sites for transcription factors or other histone modifying enzymes.
DNA甲基化由DNA甲基转移酶催化，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
PCR和细胞因子生物活性测定证实细胞因子基因整合入基因修饰细胞并通过细胞分泌相应活性蛋白产物。
PCR and cytokine bioassays verified the integration of cytokines into the modified cells and the secretion of relative protein products with activity by these cells.
PCR和细胞因子生物活性测定证实细胞因子基因整合入基因修饰细胞并通过细胞分泌相应活性蛋白产物。
PCR and cytokine bioassays verified the integration of cytokines into the modified cells and the secretion of relative protein products with activity by these cells.
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