病人接受四个疗程的紫杉醇、卡铂、依托泊苷化学治疗，每个疗程间隔3周。
Patients received four courses of chemotherapy with paclitaxel, carboplatin, and etoposide, administered at 3-week intervals.
目的：探讨依托泊苷单药维持化疗对小细胞肺癌的疗效及对生活质量的影响。
Objective:To investigate the effect of Etoposide alone maintenance chemotherapy for small cell lung cancer (SCLC).
依托泊苷能稳定酶催化性循环中的一种共价的拓扑异构酶ii裂解的DNA中间复合物，导致基因组不稳定性和细胞死亡(2,3)。
Etoposide stabilizes a covalent topoisomerase II-cleaved DNA intermediate complex in the catalytic cycle of the enzyme, leading to genomic instability and cell death (2, 3).
依托泊苷能稳定酶催化性循环中的一种共价的拓扑异构酶ii裂解的DNA中间复合物，导致基因组不稳定性和细胞死亡(2,3)。
Etoposide stabilizes a covalent topoisomerase II-cleaved DNA intermediate complex in the catalytic cycle of the enzyme, leading to genomic instability and cell death (2, 3).
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