• 致癌物代谢基因多态肿瘤遗传易感性一个重要方面

    Genetic polymorphism of carcinogen metabolizing enzymes is one of the important aspects of the genetic susceptibility to cancer.

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  • 目的研究环境暴露因素毒物代谢基因多态性对发生慢性中毒危险性影响

    Objective to explore the effects of interaction between environmental exposure factors and genetic polymorphism in toxicant metabolizing enzymes on risk of occupational chronic benzene poisoning.

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  • 糖类分解代谢酶基因作为安全标记基因,近年来植物转化中显示巨大应用潜力

    The genes coding enzymes that catalyze special sugars have showed big practical potency in plant transformation as safe marker genes.

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  • 所有表达差异基因中,随着时间进展表达持续上调基因共128条,其中成脂相关基因10条,代谢酶基因46条,炎症相关基因15条、凋亡相关基因10条,纤维化相关基因16条

    Of all the differently expressed genes, the number of up-regulated genes was 128, including 10 lipogenic genes, 46 metabolic genes, 15 inflammation genes, 10 apoptosis genes, and 16 fibrosis genes;

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  • 大学教堂医学院基因教授介绍,WilhelmsenCYP2E1大脑工作而这不是酒精代谢主要地方。

    The CYP2E1 enzyme works in the brain, which is not the major player in alcohol metabolism, says Wilhelmsen, a genetics professor at the University of North Carolina-Chapel Hill School of Medicine.

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  • 因此,确认那些可以消化纤维素的基因,然后修改重组这些基因形成新的代谢途径就可以生成一些系统能够消化株植物,并转化乙醇

    Identifying the genes for the enzymes that do this, modifying them and assembling them into new pathways would produce systems that could digest the whole plant and turn it into ethanol.

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  • 大部分酒精成瘾问题关联基因酒精脱氢基因(ALDH),参与酒精的新陈代谢作用同时过量饮酒产生保护

    Most consistently associated with alcoholism are the alcohol dehydrogenase genes (ALDH), which are involved in alcohol metabolism and protection against heavy drinking.

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  • 人类基因,也个曾用来分泌帮助维生素C代谢消化结构(L-gulonolactoneoxidase)。

    Humans have structures in their genetic make-up that were once used to produces enzymes to process vitamin C (it is called L-gulonolactone oxidase).

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  • 差异表达基因的功能涉及细胞生长增殖调控凋亡、细胞周期、应激反应转运代谢等方面。

    The expressions of the various genes modulated cell growth and proliferation, apoptosis, cell cycle, stress response, transporters, chaperones, transcription regulation and drug metabolism.

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  • 目的观察清肝活血酒精肝病乙醇代谢关键基因表达影响。

    Objective: To observe the effect of Qinggan Huoxue Decoction on gene expression of key enzyme about alcohol metabolism of Wistar rat with alcoholic liver disease (ALD).

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  • 甘油三酯脂肪酶基因家族成员包括LPLHL胰脂等,他们均参与脂蛋白代谢,其中,LPL和HL专司甘油三酯和磷脂的水解,血管内皮表面发挥作用。

    They all involve into the metabolize of lipoprotein. LPL and HL are in charge of thehydrolyze of triglyceride and phospholipid on the surface of vessel endothelium.

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  • 目的研究外源性化学物代谢酶DNA损伤修复基因多态性焦炉作业工人外周血淋巴细胞DNA损伤易感性关系。

    Objective To investigate the association of polymorphisms of metabolic and DNA repair enzyme genes and DNA damage in peripheral blood lymphocytes in coke-oven workers.

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  • 色素代谢途径关键基因研究一直花色分子育种工作的主要研究对象其中F 3'5 'H基因蓝色花卉育种的研究热点。

    These key enzyme genes in the anthocyanidin synthesis pathway were research objects of flower color molecular breeding work, and F3 '5h was the target gene of blue flower breeding research.

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  • 目的探讨致癌物代谢有关甘肽转硫GSTT1M1基因多型性与哈萨克食管癌易感性的关系。

    Objective To explore the association between genetic polymorphisms of glutathione S-transferase (GST) M1 and T1 and susceptibility to Kazak population esophageal cancer (EC).

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  • 药物代谢转运体及药物作用靶点存在着基因多态性与药物疗效毒性个体差异有很大关系

    The genetic polymorphism of drug metabolizing enzyme, transporter and target greatly influence the individual difference of drug efficiency and toxicity.

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  • 同翅害虫抗性机制主要包括代谢抗性靶标抗性,其中前者分子水平上多涉及基因扩增

    The resistance mechanisms of homopteran pests to insecticides included metabolic resistance and target resistance, and the former was mainly involved in esterase gene amplification.

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  • 结论致石饲料作为一种环境因素能揭示C57LAKR肝脏胆固醇代谢调节基因表达特征。

    Conclusions The lithogenic diet as an environmental challenge unmasked phenotypes of mRNA expression of hepatic cholesterol metabolism regulatory enzymes of C57L and AKR mice.

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  • 随着萜类吲哚生物代谢途径一些关键酶基因克隆,使得利用代谢工程植物细胞生产这些生物碱成为可能。

    With some key enzymes being cloned in the TIAs biosynthetic pathway, it is possible to produce the alkaloids in the plant cell by the metabolic engineering.

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  • 表达昼夜节律时钟基因部分联素代谢途径的肝脏测试的RNA,蛋白质活性水平

    The circadian expression of clock genes and components of adiponectin metabolic pathway in the liver was tested at the RNA, protein, or enzyme activity level.

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  • 遗传因素包括细胞增殖因子、转录因子影响叶酸代谢关键基因

    The genetic factors include cell growth factors, transformation factors and key enzymic genes involved in folate metabolism.

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  • 人群中DNA存在多态性药物反应相关基因多态性可能产生药物效应的个体差异,例如药物代谢、药物作用受体以及其它一些疾病相关基因等。

    Polymorphisms exist in human genomic DNA. And some polymorphisms such as metabolic enzymes, drug receptors, and some other genes correlated with diseases may affect the drug responsiveness.

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  • 据此推测醇化基因虫体寄生过程细胞内物质的代谢能量产生关键作用

    In conclusion, the enolase gene plays a key role in the process of cell metabolism and energy generation in their life.

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  • CYP450的合成遗传基因调控,一旦基因发生变异,它所调控合成的CYP450所催化的药物代谢即发生变化

    CYP450 is regulated by genetic genes. Once the gene mutates, the CYP450 enzyme that coded and the drug metabolism then will change.

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  • 前期试验采用芯片杂交技术从星星草中筛选出一批盐碱胁迫下高丰度表达基因其中包括代谢过程中的关键gapdhOPDR

    Previously we have screened some highly expressed genes on saline-alkaline stress by microarray technology, including the key enzymes of metabolism GAPDH and OPDR.

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  • 脂蛋白脂肪(LPL)脂蛋白代谢关键,LPL基因异常可导致异常脂蛋白血症

    Lipoprotein lipase (LPL) is a key enzyme of lipid metabolism, its primary function is the hydrolysis of the core triglycerides of circulating chylomicrons and very low density lipoproteins.

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  • 近年来的研究发现脂肪酸可以调控一些编码代谢关键基因表达脂肪酸的生化合成氧化起独特的调控作用。

    Researches indicated that from affecting gene expression, the fatty acids could have important regulation effects on metabolism, growth and cell differentiation.

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  • 亚当找到了新陈代谢模型豁口尤其是科学家认为这样的酵存在,没有基因联系上。

    Adam sought out gaps in the metabolism model, specifically orphan enzymes, which scientists think exist, but which haven't been linked to any parent genes.

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  • 通过基因工程方法提高活性氧清除活性,从而提高植物氧化胁迫的能力研究代谢途径以及抗坏血酸-谷循环中的作用奠定基础。

    Thus sharpens the ability of the anti-oxidation forces and it would be also helpful to get more information about the role of APX playing in AsA-GSH cycle and its metabolism pathway.

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  • 目的研究与致癌物有关代谢酶细胞色素P45 02E1CYP 2E1)基因多态性和饮酒肺癌易感性的关系。

    Object: To investigate the genetic polymorphism of human cytochrome P4502E1(CYP 2E1) as a susceptible factor for lung cancer.

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  • 目的研究与致癌物有关代谢酶细胞色素P45 02E1CYP 2E1)基因多态性和饮酒肺癌易感性的关系。

    Object: To investigate the genetic polymorphism of human cytochrome P4502E1(CYP 2E1) as a susceptible factor for lung cancer.

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