致癌物代谢酶基因多态是肿瘤遗传易感性的一个重要方面。
Genetic polymorphism of carcinogen metabolizing enzymes is one of the important aspects of the genetic susceptibility to cancer.
目的研究环境暴露因素与毒物代谢酶基因多态性对发生慢性苯中毒危险性的影响。
Objective to explore the effects of interaction between environmental exposure factors and genetic polymorphism in toxicant metabolizing enzymes on risk of occupational chronic benzene poisoning.
糖类分解代谢酶基因作为安全标记基因,近年来在植物转化中显示了巨大应用潜力。
The genes coding enzymes that catalyze special sugars have showed big practical potency in plant transformation as safe marker genes.
在所有表达差异的基因中,随着时间进展表达持续上调的基因共128条,其中成脂相关基因10条,代谢酶基因46条,炎症相关基因15条、凋亡相关基因10条,纤维化相关基因16条;
Of all the differently expressed genes, the number of up-regulated genes was 128, including 10 lipogenic genes, 46 metabolic genes, 15 inflammation genes, 10 apoptosis genes, and 16 fibrosis genes;
北卡大学教堂山医学院的基因教授介绍说,WilhelmsenCYP2E1酶在大脑中工作,而这并不是酒精代谢的主要地方。
The CYP2E1 enzyme works in the brain, which is not the major player in alcohol metabolism, says Wilhelmsen, a genetics professor at the University of North Carolina-Chapel Hill School of Medicine.
因此,确认那些可以消化纤维素的酶的基因,然后修改并重组这些基因形成新的代谢途径,就可以生成一些系统,能够消化整株植物,并将其转化为乙醇。
Identifying the genes for the enzymes that do this, modifying them and assembling them into new pathways would produce systems that could digest the whole plant and turn it into ethanol.
大部分与酒精成瘾问题关联的基因是酒精脱氢酶基因(ALDH),它参与酒精的新陈代谢作用同时对过量饮酒产生保护。
Most consistently associated with alcoholism are the alcohol dehydrogenase genes (ALDH), which are involved in alcohol metabolism and protection against heavy drinking.
人类的基因中,也有一个曾用来分泌帮助维生素C代谢的消化酶的结构(L-gulonolactoneoxidase)。
Humans have structures in their genetic make-up that were once used to produces enzymes to process vitamin C (it is called L-gulonolactone oxidase).
差异表达的基因的功能涉及细胞生长增殖调控、凋亡、细胞周期、应激反应、转运及代谢酶等方面。
The expressions of the various genes modulated cell growth and proliferation, apoptosis, cell cycle, stress response, transporters, chaperones, transcription regulation and drug metabolism.
目的:观察清肝活血方对酒精性肝病大鼠乙醇代谢关键酶基因表达的影响。
Objective: To observe the effect of Qinggan Huoxue Decoction on gene expression of key enzyme about alcohol metabolism of Wistar rat with alcoholic liver disease (ALD).
甘油三酯脂肪酶基因家族成员包括LPL、HL和胰脂酶等,他们均参与脂蛋白的代谢,其中,LPL和HL专司甘油三酯和磷脂的水解,在血管内皮表面发挥作用。
They all involve into the metabolize of lipoprotein. LPL and HL are in charge of thehydrolyze of triglyceride and phospholipid on the surface of vessel endothelium.
目的研究外源性化学物代谢酶和DNA损伤修复酶基因多态性与焦炉作业工人外周血淋巴细胞DNA损伤易感性的关系。
Objective To investigate the association of polymorphisms of metabolic and DNA repair enzyme genes and DNA damage in peripheral blood lymphocytes in coke-oven workers.
花色素苷代谢途径中关键酶基因的研究一直是花色分子育种工作的主要研究对象,其中F 3'5 'H基因是蓝色花卉育种的研究热点。
These key enzyme genes in the anthocyanidin synthesis pathway were research objects of flower color molecular breeding work, and F3 '5h was the target gene of blue flower breeding research.
目的为探讨与致癌物代谢有关的谷胱甘肽转硫酶(GST)T1和M1基因多型性与哈萨克族食管癌易感性的关系。
Objective To explore the association between genetic polymorphisms of glutathione S-transferase (GST) M1 and T1 and susceptibility to Kazak population esophageal cancer (EC).
药物代谢酶、转运体及药物作用靶点存在着的基因多态性与药物疗效和毒性的个体差异有很大关系。
The genetic polymorphism of drug metabolizing enzyme, transporter and target greatly influence the individual difference of drug efficiency and toxicity.
同翅目害虫的抗性机制主要包括代谢抗性和靶标抗性,其中前者在分子水平上多涉及酯酶基因扩增。
The resistance mechanisms of homopteran pests to insecticides included metabolic resistance and target resistance, and the former was mainly involved in esterase gene amplification.
结论致石饲料作为一种环境因素能揭示C57L和AKR鼠肝脏胆固醇代谢调节酶的基因表达特征。
Conclusions The lithogenic diet as an environmental challenge unmasked phenotypes of mRNA expression of hepatic cholesterol metabolism regulatory enzymes of C57L and AKR mice.
随着萜类吲哚生物碱代谢途径中一些关键酶基因被克隆,使得利用代谢工程在植物细胞中生产这些生物碱成为可能。
With some key enzymes being cloned in the TIAs biosynthetic pathway, it is possible to produce the alkaloids in the plant cell by the metabolic engineering.
表达的昼夜节律时钟的基因和部分脂联素代谢途径的肝脏是测试的RNA,蛋白质,或酶活性水平。
The circadian expression of clock genes and components of adiponectin metabolic pathway in the liver was tested at the RNA, protein, or enzyme activity level.
遗传因素中包括细胞增殖因子、转录因子及影响叶酸代谢的关键酶的基因。
The genetic factors include cell growth factors, transformation factors and key enzymic genes involved in folate metabolism.
人群中DNA存在多态性,与药物反应相关的基因多态性可能产生药物效应的个体差异,例如药物代谢酶、药物作用受体以及其它一些与疾病相关基因等。
Polymorphisms exist in human genomic DNA. And some polymorphisms such as metabolic enzymes, drug receptors, and some other genes correlated with diseases may affect the drug responsiveness.
据此推测该烯醇化酶基因在虫体寄生过程中对细胞内物质的代谢与能量的产生起关键作用。
In conclusion, the enolase gene plays a key role in the process of cell metabolism and energy generation in their life.
CYP450的合成受着遗传基因的调控,一旦基因发生变异,它所调控合成的CYP450酶及酶所催化的药物代谢即发生变化。
CYP450 is regulated by genetic genes. Once the gene mutates, the CYP450 enzyme that coded and the drug metabolism then will change.
前期试验采用芯片杂交技术从星星草中筛选出了一批在盐碱胁迫下高丰度表达的基因,其中包括代谢过程中的关键酶gapdh和OPDR。
Previously we have screened some highly expressed genes on saline-alkaline stress by microarray technology, including the key enzymes of metabolism GAPDH and OPDR.
脂蛋白脂肪酶(LPL)是脂蛋白代谢的关键酶,LPL基因变异常可导致异常脂蛋白血症。
Lipoprotein lipase (LPL) is a key enzyme of lipid metabolism, its primary function is the hydrolysis of the core triglycerides of circulating chylomicrons and very low density lipoproteins.
近年来的研究发现,脂肪酸可以调控一些编码代谢关键酶的基因表达,对脂肪酸的生化合成和氧化起独特的调控作用。
Researches indicated that from affecting gene expression, the fatty acids could have important regulation effects on metabolism, growth and cell differentiation.
亚当找到了新陈代谢模型的豁口,尤其是孤酵酶。科学家认为有这样的酵酶存在,但没有把它与源基因联系上。
Adam sought out gaps in the metabolism model, specifically orphan enzymes, which scientists think exist, but which haven't been linked to any parent genes.
通过基因工程的方法提高活性氧清除酶活性,从而提高植物的抗氧化胁迫的能力,并为研究其代谢途径以及在抗坏血酸-谷胱甘肽循环中的作用奠定基础。
Thus sharpens the ability of the anti-oxidation forces and it would be also helpful to get more information about the role of APX playing in AsA-GSH cycle and its metabolism pathway.
目的:研究与致癌物有关的代谢酶细胞色素P45 02E1(CYP 2E1)基因多态性和饮酒与肺癌易感性的关系。
Object: To investigate the genetic polymorphism of human cytochrome P4502E1(CYP 2E1) as a susceptible factor for lung cancer.
目的:研究与致癌物有关的代谢酶细胞色素P45 02E1(CYP 2E1)基因多态性和饮酒与肺癌易感性的关系。
Object: To investigate the genetic polymorphism of human cytochrome P4502E1(CYP 2E1) as a susceptible factor for lung cancer.
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