我妈妈责备我的不稳定基因前夫继承。
My mum blames my unstable gene inherited from her ex-husband.
加的夫公共健康实验室从一株分离株中克隆了病毒的拷贝，让我们去识别能引起体外病毒不稳定的基因。
Cloning a copy of the virus from a strain isolated by Cardiff Public Health Laboratories has enabled us to identify the genes causing the instability of the virus outside the body.
这其中包括钠通道基因scn5a的突变，该基因以前发现与LQTS、其他不稳定心律失常以及猝死相关。
These included mutations in the sodium channel gene SCN5A, previously associated with LQTS and other unstable heart rhythm conditions and sudden death.
结论：乙酸镍能诱发16hbe细胞基因组不稳定。
CONCLUSION: Crystalline nickel sulfide could induce genomic instability in the 16hbe cells induced by nickel acetate.
因此肿瘤细胞基因不稳定可能与中心体异常密切相关。中心体异常是恶性肿瘤细胞的普遍特征。
So gene instability of tumor cells may be closely correlated with centrosome abnormality, which is a common feature of malignant tumor cells.
双链断裂得不到修复，细胞将会死亡或发生染色体断裂、丢失，若是错误修复将导致基因突变或基因组不稳定，增加癌症的风险度。
If not repaired, the breakage can result in lethality or chromosome breakage, and if misrepaired, it can cause mutation, gene instability and the increased rate of tumorigenesis.
由于错配修复基因缺陷而导致的基因组不稳定，被认为是导致肿瘤发生的一条新途径。
The instability of genome which results from defect of MMR genes is thought as a new oncogenesis way.
结论黑色素瘤的发生可能与基因组不稳定性有关。
Conclusion The occurrence of melanoma might be associated with genetic genomic instability.
双螺旋上并发生断裂，使得基因组变得更不稳定。
Breaks appear in the double helix, destabilizing the genome further.
环境与基因型互作的差异性导致了花粉败育的年度不稳定性。
The difference in the interaction between environment and genotype reflected on the unstability of pollen abortion in different years.
由以上结果可知，SR 1耐盐性的提高是不稳定的，其耐盐性的提高并非基因突变引起。
These suggest that the salt tolerance of SR1 is not stable; its increase of salt tolerance was a physiological adaptation, not mutation.
依托泊苷能稳定酶催化性循环中的一种共价的拓扑异构酶ii裂解的DNA中间复合物，导致基因组不稳定性和细胞死亡(2,3)。
Etoposide stabilizes a covalent topoisomerase II-cleaved DNA intermediate complex in the catalytic cycle of the enzyme, leading to genomic instability and cell death (2, 3).
研究目的遗传的不稳定性是肿瘤生成的最重要的因素之一，而染色体的精确分离是基因物质稳定遗传关键。
Objective genetic instability is one of the most important factors to underlie neoplasia, and precise segregation of the chromosome is critical for stable inheritance of genetic material.
反转录转座子是植物中最不稳定的遗传元件之一，它们对基因组的大小、结构、功能和进化都有重要作用。
Retrotransposons are one of the most unstable genetic elements in the plant kingdom, they have the potential to dramatically affect gene function and host genome structure.
而AT M基因遗传不稳定性可能参与慢粒急淋变过程。
The genetic instability of ATM gene may play an important role in the evolution of CML to ALL.
目的：了解基质金属蛋白酶9基因C1562T多态性与中国南方汉族人群不稳定型心绞痛易感性的关系。
AIM: to investigate the association between the matrix metalloproteinase-9 (MMP-9) gene C1562T polymorphism and the susceptibility to unstable angina pectoris (UAP) in Han population of South China.
这种肿瘤显示为微卫星不稳定性，一种获得性基因特征暗示DNA修复机制缺陷。
Such tumors display microsatellite instability, an acquired genetic characteristic that indicates defects in DNA-repair machinery.
近年来，很多研究者发现上述持家基因的表达水平并不稳定，利用它们作为内标来定量并不准确。
But in recent year, many researchers observed that the expression of housekeeping gene was not stable at all conditions.
基因组不稳定是人类肿瘤的特征。
有很多原因可以解释，包括：乏氧驱使基因组不稳定性及改变DNA损伤修复通路的能力。
There are several reasons why this might be, including the capacity of hypoxia to drive genomic instability and alter DNA damage repair pathways.
DNA损伤反应机制的任何功能缺陷将会引起基因组的不稳定性，从而导致癌症的发生。
Defects in DNA damage response can cause genome instability, which induces many human cancers.
错配修复基因功能缺失时，细胞常会因基因突变聚集而表现为遗传不稳定。
When function defects of mismatch repair genes, Cell Showes Genomic instability because of the aggregation of mutation.
错配修复基因功能缺失时，细胞常会因基因突变聚集而表现为遗传不稳定。
When function defects of mismatch repair genes, Cell Showes Genomic instability because of the aggregation of mutation.
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