环腺苷酸结合蛋白激酶的调节亚基:一个磷酸化蛋白激酶磷酸化酶激酶。
Cyclic AMP binds to the regulatory subunit of protein kinase A: Protein kinase A phosphorylates phosphorylase kinase.
蛋白激酶是数量最多的一类激酶,作用和修饰特定蛋白的活性。
The largest group of kinases are protein kinases, which act on and modify the activity of specific proteins.
细胞外信号调节激酶是丝裂原激活蛋白激酶家族的重要成员。
The extracellular signal-regulated kinase(ERK) is an important member of mitogen-activated protein kinase(MAPK) family.
激酶缓冲液用来分析蛋白激酶的活性。
丝裂原激活的蛋白激酶又称细胞外信号调节激酶,具有神经元信号传导功能,参与多种发育过程。
Mitogen activated protein (MAP) kinase, also known as extracellular signal regulated kinase, or ERK, functions in neuronal signal transduction and participates in diverse development processes.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂,能阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
结果表明:阿维链霉菌中存在61个组氨酸蛋白激酶,其中30个组氨酸蛋白激酶包含了全部的保守传递器结构域。
The result showed that 61 histidine kinases were found in the genome and 30 histidine kinases contained total conserved transmitter domain.
所有先天感染患儿临床株的UL145编码蛋白具有蛋白激酶(C PKC)磷酸化功能位点和酪蛋白激酶(CK2)磷酸化功能位点。
The UL145 protein of the clinical strains were conserved and comprised phosphorylation motif sites for protein kinase C(PKC) and casein kinase 2(CK2).
在调节细胞能量状态的蛋白激酶级联反应中,AMP激活的蛋白激酶(AMPK)是其中枢组成部分。
AMP-activated protein kinase AMPK is a central component of a protein kinase cascade that plays a pivotal role in the regulation of intracellular energy status.
在此,我们将总结一些已经能用于心血管疾病的蛋白激酶靶位,以及一些鉴定与心血管疾病有关蛋白激酶假定的治疗靶位的难点。
Here, we will review several kinds of protein kinases as potential targets for CVDs and some difficulty in identifying a protein kinase as a putative therapeutic target for CVDs.
下丘脑蛋白激酶C抑制剂卡马拉素和OAG同时给药会抑制OAG活化蛋白激酶c的能力并降低葡萄糖的生成。
Coadministration of hypothalamic PKC - inhibitor rottlerin with OAG prevented the ability of OAG to activate PKC - and lower glucose production.
蛋白激酶是一种可以控制其他蛋白开或是关的酶,IKKE蛋白激酶看起来是作用于调控小鼠代谢的基因的。
Protein kinases are enzymes that turn other proteins on or off. The IKKE protein kinase appears to target proteins which, in turn, control genes that regulate the mouse metabolism.
目的:研究低体温大鼠下丘脑蛋白激酶A(PKA)、蛋白激酶C(PKC)活性的变化及桂枝汤的升温作用机理。
Objective:To observe the changes of the activity of protein kinase A(PKA) and C(PKC), and further investigate the mechanisms of anti-hypothermia action of Guizhi Tang.
腺苷酸激活的蛋白激酶(AMPK)是一种在酵母,植物和动物界高度保守的蛋白激酶,它在能量平衡中发挥关键性的作用(1)。
AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis (1).
结论:AG110 9不仅是酪氨酸蛋白激酶的抑制剂,而且是一种十分有效的蛋白激酶CK2的抑制剂。
CONCLUSIONS AG1109 not only was an effective inhibitor of protein tyrosine kinases, but also was a novel potent inhibitor of protein kinase CK2.
本发明涉及可用作蛋白激酶、特别是JAK家族激酶的抑制剂的式(i)化合物。
The present invention relates to compounds of formula (I) useful as inhibitors of protein kinases, particularly of JAK family kinases.
极光激酶A(AIK)是一种调节细胞周期的丝氨酸/苏氨酸蛋白激酶,在多种肿瘤细胞系中过表达(1-3)。
Aurora A (AIK) is a cell cycle-regulated serine/threonine protein kinase that is overexpressed in many tumor cell lines (1-3).
主要观察指标:神经细丝的磷酸化程度及糖原合酶激酶3、细胞周期依赖性蛋白激酶5的酶活性。
MAIN OUTCOME MEASURES: The degree of NF phosphorylation and the activities of GSK-3 and CDK-5 were mainly observed.
主要观察指标:神经细丝的磷酸化程度及糖原合酶激酶3、细胞周期依赖性蛋白激酶5的酶活性。
MAIN OUTCOME MEASURES: The degree of NF phosphorylation and the activities of GSK-3 and CDK-5 were mainly observed.
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