最近的一些研究显示TRIM家族可能是一类新的RING指泛素连接酶。
The recent data indicating that some TRIM proteins are implicated in ubiquitination, as a novel class of RING finger ubiquitin E3 ligases.
SCF复合体是一种非常重要的E3泛素连接酶,在植物中研究的最为深入。
SCF complex is a very important ubiquitin E3 ligase which has been exploited very well in plants.
CHIP属于连接酶类,具有E3泛素连接酶活性,参与能量代谢途径和新陈代谢。
CHIP, an E3 ubiquitin ligase and cochaperones, involves in energy metabolism and protein quality control.
通过最近的努力,我们已经明确了心脏中存在的泛素连接酶在调节心肌功能中的多种作用。
Our recent efforts have defined multiple roles for ubiquitin ligases in the heart to regulate cardiomyocyte function.
由磷酸化影响的调控步骤可能与E3泛素连接酶对底物的识别有关,也可能与实际的交联反应有关。
The regulatory step affected by phosphorylation could involve either recognition of the substrate by an E3 ubiquitin ligase or the actual conjugation reaction.
泛素连接酶E3是一个种类繁多的大家族,涉及对植物生长、发育、逆境胁迫防御等多个方面关键步骤的控制。
E3 ubiquitin ligases are a large family with wide variety, and are involved in many important biological processes in plants.
在心肌细胞的功能方面,泛素连接酶的生物学性能将被总结概括,并且,其作用将会被看作为潜在的治疗目标。
The biology of ubiquitin ligases in the context of cardiomyocyte function will be summarized, and the roles for these ubiquitin ligases will be discussed as potential therapeutic targets.
乳腺癌易感基因,BRCA1,编码一种E3泛素连接酶,BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of the DNA damage response and DNA repair.
乳腺癌易感基因,BRCA1,编码一种E3泛素连接酶,BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of DNA damage response and DNA repair.
本文概述了植物干旱胁迫的调控机制、植物的泛素连接酶e3,并着重阐述了泛素连接酶e3介导的植物干旱胁迫反应及其作用机制。
In this paper, we summarized the drought stress regulation mechanism, plant ubiquitin ligase E3, and emphatically described the ubiquitin ligase E3 response to plant drought stress and its mechanisms.
本文概述了植物干旱胁迫的调控机制、植物的泛素连接酶e3,并着重阐述了泛素连接酶e3介导的植物干旱胁迫反应及其作用机制。
In this paper, we summarized the drought stress regulation mechanism, plant ubiquitin ligase E3, and emphatically described the ubiquitin ligase E3 response to plant drought stress and its mechanisms.
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