方法体外培养获取生长状态良好的兔骨髓间充质干细胞,进行成软骨诱导,观察并检测其生物学特性。
Methods Rabbit BMSCs were cultured in vitro induced to chondrocytes, and then the biologic characters of the chondrocyte were observed and tested.
骨形态发生蛋白(BMP)是一类具有高效成骨活性的蛋白质,因其能够异位诱导间充质细胞分化为软骨和骨细胞而形成新骨,在临床骨缺损修复中具有良好的应用前景。
Bone morphogenetic protein (BMP) has good potential in treatment for bone defects as it can induce mesenchymal cells to differentiate into cartilage cells and bone cells so to form new bone.
目的:评价脱钙异体骨关节(DOAA)移植诱导成骨和成软骨的作用。
Objective: To evaluate the bone and cartilage inductive capacity of demineralized osteoarticular allograft (DOAA) transplantation.
本实验主要利用骨髓基质干细胞的这一特性,对其进行成软骨和成骨诱导,建立诱导和鉴定体系;
This experiment mainly used this feature of bone marrow stromal stem cells to find ways to induce them into chondrocytes and osteoblasts, and also established the induction and appraisal system;
本实验主要利用骨髓基质干细胞的这一特性,对其进行成软骨和成骨诱导,建立诱导和鉴定体系;
This experiment mainly used this feature of bone marrow stromal stem cells to find ways to induce them into chondrocytes and osteoblasts, and also established the induction and appraisal system;
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