Mammalian reproductive ability also can be influenced potentially by TTF-1.
TTF - 1基因还对哺乳动物的繁殖性能有潜在的影响。
TTF-1 expression is most frequently seen in carcinomas of thyroid and lung origin.
最常见其在甲状腺和肺来源的癌中表达。
Thyroid transcription factor 1(TTF-1) is a homeobox domain transcription factor of the NKX2 family.
甲状腺转录因子1是含一同源盒域的转录因子,属于NKX2家族。
Objective To investigate the change of the expression of TTF-1 and SP-A in lung tissue of ALI rats induced by LPS.
目的探讨内毒素(LPS)诱导的急性肺损伤(ALI)大鼠肺组织甲状腺转录因子-1(TTF-1)、肺表面活性物质相关蛋白-A(SP-A)表达的变化。
Methods 40 patients with lung cancer were studied to detect TTF-1 gene by using reverse transcription-polymerase chain reaction assay (RT-PCR).
方法采用逆转录—聚合酶链反应(RT -PCR)方法检测40例患者的肺癌组织ttf - 1基因的表达。
Purpose to analyze the expression of thyroid transcription factor-1 (TTF-1) in the metastatic pulmonary adenocarcinoma cells in serous effusions.
目的探讨甲状腺转录因子1 (TTF 1)在浆膜腔积液肺腺癌细胞中的表达,为肺腺癌的诊断和鉴别诊断提供新的依据。
Homogeneous analysis demonstrated that nucleotide and amino acids sequences of sheep TTF-1 gene between different species mammal are comparatively conservative.
序列同源性分析表明,绵羊ttf - 1基因的核酸和蛋白质序列在不同哺乳动物之间有很高的同源性,分子在进化上均相当保守。
Objectives To study the expression of surfactant protein B(SP-B)and thyroid transcription factor 1(TTF-1)and evaluate the role in neonatal hyaline membrane disease(NHMD).
目的探讨表面活性蛋白B(SP-B)与甲状腺转录因子(TTF-1)在新生儿肺透明膜病中的表达及其意义。
TTF-1 is related to development of the thyroid gland and regulates and controls transcriptions of thyroglobulin(TG), thyroperoxidase(TPO), and thyrotropin(TSH) receptor genes.
其与甲状腺的发育有关,并且调控甲状腺球蛋白、甲状腺过氧化物酶和促甲状腺激素受体基因的转录。
Objective to investigate the biologic significance of thyroid transcription factor-1 (TTF-1) and surfactant protein a (SP-A) and SP-B expression in pulmonary sclerosing hemangioma (PSH).
目的探讨甲状腺转录因子1 (TTF 1)和表面活性蛋白a、B (SP A,SP B)在肺硬化性血管瘤(PSH)中表达的生物学意义。
Methods The TTF-1 expression intensity (in positive units, PU) in paraffin-embedded tissue blocks was determined using immunohistochemical SP method in combination with Motic Images System.
方法石蜡包埋切片,应用免疫组织化学SP法及麦克奥迪真彩色病理分析图像分析系统,对TTF-1表达强度的阳性单位(PU)进行定量分析。
TTF, 1 was expressed in the majority of benign and malignant thyroid diseases. The immnostaining of TTF, 1 was located in nuclear of cells, TTF, 1 was a sensitive marker for thyroid follicular cells.
TTF蛳1在甲状腺常见良恶性病变中阳性率均高,特异地表达在细胞核,是一种特异的甲状腺滤泡细胞标志物。
TTF, 1 was expressed in the majority of benign and malignant thyroid diseases. The immnostaining of TTF, 1 was located in nuclear of cells, TTF, 1 was a sensitive marker for thyroid follicular cells.
TTF蛳1在甲状腺常见良恶性病变中阳性率均高,特异地表达在细胞核,是一种特异的甲状腺滤泡细胞标志物。
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