The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression.
肿瘤抑制蛋白p21Waf1/Cip1可以作为细胞周期的抑制因子。
The changes in cell cycle progression of synchronized HUVECs were examined by flow cytometric analysis.
用流式细胞技术检测各组细胞周期,观察细胞增殖能力的变化。
Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression (5).
CDK介导的细胞周期依赖性磷酸化能够抑制R b靶向结合并允许细胞周期进程(5)。
Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression (5).
CDK引起的细胞周期依赖性磷酸化会抑制Rb与靶蛋白结合从而促进细胞周期的进行(5)。
Objective To explore the relationship between cell cycle progression and high radiosensitivity of AT5BIVA cells.
目的研究AT细胞辐射高敏感性与细胞周期进程间的联系。
In the present study, the effect of X rays on el 4 cell doubling time and cell cycle progression were investigated.
目的研究不同剂量X射线照射对EL4淋巴瘤细胞周期进程及细胞倍增时间的影响。
Studies have shown that abnormal control of cell cycle progression is a significant Characteristic of malignant tumors.
研究表明细胞周期调控异常是恶性肿瘤的一个重要特征。
This review focuses on the regulation of CAK activity via its three subunits and its regulation on the cell cycle progression.
本文主要就CAK自身活性调节及其对细胞周期的调控进展作一综述。
Cell cycle progression is regulated by a wide variety of external factors, in which reactive oxygen species (ROS) may play an important role.
细胞周期进程由多种外界因素调控,活性氧可能在细胞周期进程中发挥重要作用。
Objective: to observe the dose rate effect of adaptive response of thymocyte apoptosis and cell cycle progression induced by low dose X ray radiation.
目的:观察X线低剂量辐射诱导胸腺细胞凋亡和细胞周期进程适应性反应的剂量率效应。
OBJECTIVE: To investigate the antitumor activity of compound G and J, two kinds of gibberellin derivatives and their effect on cell cycle progression.
目的研究新四环二萜类化合物G和J的抗肿瘤作用及对细胞周期分布的影响。
In normal cells, p21 ACTS like a brake to block cell cycle progression in the event of DNA damage, preventing the cells from dividing and potentially becoming cancerous.
在正常的细胞中,如果DNA受损,p21就会像刹车一样阻断细胞周期进程以防止细胞分裂和癌变。
Its scope of the science spans such diverse areas as cell cycle progression, cell differentiation, oncogenesis, chromosome biology, neuronal guidance and stem cell biology.
该所的科学范围涉及细胞周期,细胞分化,肿瘤形成,染色体生物学,神经元引导,和干细胞生物学等多个领域。
This study identifies the major deubiquitinase for histone H2A and demonstrates that H2A deubiquitination is critically involved in cell cycle progression and gene expression.
本研究确定了主要的组蛋白h 2 A去泛素和表明H2A去泛素化是至关重要参与细胞周期进程和基因表达。
It is obviously down-regulated in nasopharyngeal carcinoma (NPC) cells and tissues. Over expression of BRD7 in NPC cells can inhibit cell proliferation and cell cycle progression.
它在鼻咽癌细胞和组织中表达明显下调,过表达BRD7基因可抑制鼻咽癌细胞的生长和细胞周期的进程。
Purpose to investigate the effects of DNA methylation and histone acetylation on the expression of tumor associated genes and cell cycle progression in human colonic cancer cells.
目的观察dna甲基化和组蛋白乙酰化对人结肠癌细胞系癌相关基因的表达和细胞周期的影响。
Cell Cycle Progression through the cell division cycle and transitions between various phases are regulated by using CDC25 phosphatases to activate specific cyclin-dependent kinase(CDK) complexes.
细胞分裂周期运行和不同时相的转换通过CDC25磷酸酶去磷酸化和激活周期蛋白依赖性激酶(CDK)复合物来调控。
This mechanism of action has been shown to delay progression of the cell cycle through the late s and early G2 phase (4, 5).
这种作用机制能通过S晚期和G2早期来延误细胞周期的进展(4,5)。
This research reveals that SPATA4 gene can inhibit cellular senescence and apoptosis as well as promote the progression of cell cycle and cell proliferation;
本研究发现SPATA4基因能够抑制细胞衰老和细胞凋亡、促进细胞周期的推进与细胞增殖;
The Deubiquitinating Enzyme USP17 Is Highly Expressed in Tumor Biopsies, Is Cell Cycle Regulated, and Is Required for G1-S Progression.
泛素酶usp17在肿瘤活检标本中高表达,受细胞周期调节,且是细胞由G 1期进入S期的必需者。
Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle.
周期素d 1编码一种全酶的调节亚单位,该酶利用蛋白磷酸化灭活视网膜母细胞瘤蛋白,通过细胞周期G 1 - S期促进肿瘤进展恶化。
Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle.
周期素d 1编码一种全酶的调节亚单位,该酶利用蛋白磷酸化灭活视网膜母细胞瘤蛋白,通过细胞周期G 1 - S期促进肿瘤进展恶化。
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