The genetic change, known as a partial tandem duplication, is located in a gene called MLL (for mixed-lineage leukemia).
该基因改变,即所谓的部分串联复制,位于MLL(混合血系白血病)基因上。
A partial tandem duplication is a type of gene mutation that occurs when a section of a gene is repeated, like a stutter in the gene's DNA.
部分串联复制是基因突变的一个类型,当一个基因片断重复时发生,就像停顿基因。
FLT3 Internal tandem duplication (ITD) and tyrosine kinase domain (TKD) mutations are seen in 30% of AML patients (PTS) and are associated with poor survival.
30%的急性髓系白血病(aml)患者发生FLT3内部串联重复(itd)和酪氨酸激酶域(TKD)突变,而且生存预后较差。
This study was to explore the clinical significance of FLT3 internal tandem duplication (FLT3/ITD) in acute myeloid leukemia (AML) with chromosome abnormality.
本研究旨在探讨伴有染色体异常急性髓系白血病患者FLT3跨膜区内部串联重复突变检测的临床意义。
This study was to explore the clinical significance of FLT3 internal tandem duplication (FLT3/ITD) in acute myeloid leukemia (AML) with chromosome abnormality.
本研究旨在探讨伴有染色体异常急性髓系白血病患者FLT3跨膜区内部串联重复突变检测的临床意义。
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