• Like we talked about with insulin; make large quantities of this recombinant viral protein, and use that as a vaccine.

    就像我们讲过的胰岛素,生成大量重组的病毒蛋白,并将其作为疫苗使用

    耶鲁公开课 - 生物医学工程探索课程节选

  • So if it's not a cell that's going through division you can't use a retrovirus to express the protein.

    如果细胞不在分裂阶段,你就不能用逆转录病毒来表达某个蛋白

    耶鲁公开课 - 生物医学工程探索课程节选

  • It could have been corrupted because a virus was inside of it so it was making foreign proteins.

    细胞被损害的原因是,病毒在其中生产了外源蛋白

    耶鲁公开课 - 生物医学工程探索课程节选

  • I just have to produce many, many copies of a piece of the virus, a protein, say.

    只需要制造许许多多,病毒片段和蛋白的拷贝

    耶鲁公开课 - 生物医学工程探索课程节选

  • They basically make many, many copies of their DNA and they make all of their viral proteins and they assemble into new viral units.

    它们会生成不计其数的病毒基因拷贝,并翻译生成病毒蛋白,组装成新的病毒单位

    耶鲁公开课 - 生物医学工程探索课程节选

  • We've talked about killing a virus by cross-linking it, for example, to make a substance that looks like a vaccine-- looks like a virus but can't replicate.

    例如,我们谈论过,通过蛋白交联来杀死病毒,以便制造出一种类似疫苗,应该是类似病毒但却无法进行复制的物质

    耶鲁公开课 - 生物医学工程探索课程节选

  • The proteins that are produced by genes that are on the viral genome get transcribed and translated in order to make more structural proteins that are needed for assembly of the virus.

    病毒基因组上的基因,通过转录和转译制造出来的蛋白质,以便可以制造出更多的,被病毒组合所需的结构蛋白

    耶鲁公开课 - 生物医学工程探索课程节选

  • They, in some cases, they integrate their DNA into the host chromosome, that's what retroviruses do and they make viral proteins.

    有些情况下,病毒DNA会整合进宿主的染色体中,逆转录病毒就是这样做的,它们还制造病毒蛋白

    耶鲁公开课 - 生物医学工程探索课程节选

  • The other thing that it does is that when a virus is inside these cells making its proteins, some of those proteins get processed or digested into small fragments that are themselves antigens.

    HC的另一项作用是,当病毒在细胞内表达蛋白时,一些蛋白被加工,或者,分解成小片段而成为抗原

    耶鲁公开课 - 生物医学工程探索课程节选

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