• So notice a difference in these structures, is this has an n h bond whereas this has an o h bond.

    注意它们之间的有一点不同,那就是一个有氮氢键,而另一个有氧氢键

    麻省理工公开课 - 化学原理课程节选

  • There's not actually chemical covalent bonds that are formed but it's a non-covalent interaction, usually dominated by hydrogen bonding.

    所以配体和受体之间不生成共价键,这是一种非共价化合反应,它们通常以氢键相联

    耶鲁公开课 - 生物医学工程探索课程节选

  • Now if you read in the book, you read about where this figure is shown in the book, you can understand more about why these structures line up in the right way so that the right molecular elements are together to form hydrogen bonding pairs between them.

    如果你预习过课本,课本中有关于这些详细的描述,你可以更深刻的理解,为什么这些结构是采用这种连接方式,以使对应的分子部分靠近,并形成氢键连接

    耶鲁公开课 - 生物医学工程探索课程节选

  • Now remember that only appears in DNA and appears in RNA, and so can also form a hydrogen binding pair with .

    还要记住T只出现在DNA中,而U出现在RNA中,U和A也可以通过氢键结合就可以了

    耶鲁公开课 - 生物医学工程探索课程节选

  • That tells you something about the physical chemistry of the molecule; that it's these hydrogen bonds that hold the double strands and I can break those down under certain conditions.

    我们从中可以知道一些,DNA分子的理化特点,双链是由氢键连接在一起,在一定条件下这些氢键可以断裂

    耶鲁公开课 - 生物医学工程探索课程节选

  • That's because you have to satisfy this base pair matching in order to have hydrogen bonding in each of the struts of the ladder in order to form a stable structure.

    NA双链要满足互补配对原则,以使碱基对之间,形成氢键,从而形成稳定的双链结构

    耶鲁公开课 - 生物医学工程探索课程节选

  • The native structure is this double stranded structure here and if I heat it up slightly and I add some base, so under slightly basic conditions, these molecules will fall apart because you've created conditions where the hydrogen bonding is no longer favorable so they peel apart.

    原始结构,在这里就是指DNA双链,如果我稍微加热,并且加入一些碱,在弱碱性的条件下,这些配对碱基会分开,这是因为在一定条件下,碱基对之间的氢键,不再稳定并且会断裂分开

    耶鲁公开课 - 生物医学工程探索课程节选

  • If I had a beaker sitting on the table here and it contained a million blue double stranded DNA molecules and a million red double stranded DNA molecules and I heated it up and added a little base, I'd soon have four million individual strands just floating around in the solution because I've broken up this hydrogen bonding and the DNA molecules fall apart.

    假如我这里有一个烧杯 里面,盛有一百万条蓝色DNA双链和,一百万条红色DNA双链,然后我稍微加热一下烧杯,并且加一些碱,很快我就有了四百万条DNA单链,漂浮在溶液里,因为我已经使得氢键断裂,DNA双链也随之打开

    耶鲁公开课 - 生物医学工程探索课程节选

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