It's not self-renewing, in that division of the zygote results in two daughter cells that are no longer the zygote anymore, they're down some pathway.

它是不会自我更新的,受精卵分裂后成了两个子细胞,而这两个子细胞就不再是受精卵了,它们沿着某种路径进行了分化

耶鲁公开课 - 生物医学工程探索课程节选