• So why don't you tell me what the formal charge should be on the sulfur atom of thionyl chloride?

    那么请大家来告诉我亚硫酰氯中,的硫原子应该有多少形式电荷?

    麻省理工公开课 - 化学原理课程节选

  • actually our third, but the second one we're going to talk about in terms of formal charge, which is thionyl chloride.

    实际上是第三个,但它是第二个,形式电荷的例子,也就是亚硫酰氯。

    麻省理工公开课 - 化学原理课程节选

  • So again, we should be able to check all of our formal charges and make sure they add up to 0, which they do, and that makes sense, because we have a neutral atom in terms of thionyl chloride.

    因此同样地,我们可以检验一下,我们所有的形式电荷是否正确,确保它们加起来等于零,而它们确实是这样,这是合理的,因为亚硫酰氯是一个中性原子。

    麻省理工公开课 - 化学原理课程节选

  • So, which atom would you expect to be in the center of a Lewis structure for thionyl chloride?

    那么,大家认为那个原子应该在,亚硫酰氯的路易斯结构的中心位置呢?

    麻省理工公开课 - 化学原理课程节选

  • And the last example that we're going to talk about is thionyl chloride, so it's s o c l 2. This is another good step forward, because now we actually have four different atoms in our molecule.

    我们要讨论的最后一个例子,是氯化亚砜,就是硫,氧,氯,二,这又是一个进步,因为我们的分子中现在有四个不同的原子了。

    麻省理工公开课 - 化学原理课程节选

  • And what's important to keep in mind about formal charge is if we have a neutral atom, such as we did in thionyl chloride here, the sum of the individual formal charges on individual atoms within the molecule have to equal 0.

    而关于形式电荷记住一点是很重要的,那就是如果我们有一个中性原子,比如亚硫酰氯,那么这个分子中的所有原子的,形式电荷之和应该等于零。

    麻省理工公开课 - 化学原理课程节选

  • I'll tell you a little about thionyl chloride as well.

    关于亚硫酰氯,我也会给大家简单介绍一下。

    麻省理工公开课 - 化学原理课程节选

  • But in terms of drugs that don't look like maybe this compound was used in the synthesis, many of them might have used thionyl chloride, because it generates such a nice reactive intermediate that you can go on and make a bunch of different compounds from that intermediate.

    但是对于药物来说,它们可能跟合成过程中用到的这种化合物并不相像,很多药物的制造过程中都会用到亚硫酰氯,因为它能产生活性如此之高的反应中间体,以至于你可以继续利用反应中间体,来制造一堆不同类型的化合物。

    麻省理工公开课 - 化学原理课程节选

  • So, for example, Wellbutrin, it is very unlikely that it would have thionyl chloride in order to make it, and if thionyl chloride was used at some point in the synthesis, it was not to put that chlorine atom on, it was to put something else on.

    比如,安非他酮,用亚硫酰氯来制造它,是不太可能的,而就算在合成过程中的某一阶段用到了亚硫酰氯,它也不会把氯原子加进去,而是把其它东西加进去。

    麻省理工公开课 - 化学原理课程节选

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