In order to attract the rabbit's own stem cells to re-grow the cartilage, channels in the scaffold were filled with a growth factor protein.
VOA: standard.2010.08.11
It's not the best form of food in that they're actually very poor in protein, and unfortunately very, very rich in cyanide.
但木薯的根并不是最好的食物,因为它的蛋白质含量很少,而更不幸的是,它的氰化物含量非常,非常高。
So if it's not a cell that's going through division you can't use a retrovirus to express the protein.
如果细胞不在分裂阶段,你就不能用逆转录病毒来表达某个蛋白
The reason it is so exciting that it's a protein, and it's a protein, this is the structure here, it's a ribbon structure so you can kind of see what it looks like, it's made up of all natural amino acids.
它这么让人激动的原因是因为它是一个蛋白质,这里的这个结构,这是个带状机构,你可以看到它的样子,它全部是由氨基酸组成的。
The macro nutrients are the big constituents of food, that's protein, carbohydrate, and fat.
大量营养素是食物重要组成来源,即蛋白质,碳水化合物和脂肪
What a kinase enzyme does is that it recognizes this protein, and for example, the tyrosine that's on the protein.
激酶能够识别这类蛋白,例如,包含酪氨酸的蛋白
If you could introduce that gene you'd make the chemical, in this case it's a protein called vascular endothelial growth factor.
通过导入一种生成特殊化学物质的基因,这种疗法中指的是一种蛋白,叫做血管内皮生长因子
And it's neat to see the glowing jellyfish and think about the fluorescent protein that's in them.
你可以看到整齐的水母,而且考虑它里面的蛋白质。
Essentially, what they are is it's a protein that spans the membrane of a cell.
本质上来说,它是一个横跨细胞膜的蛋白质。
In fact, for insulin, it's not the final version of the protein that comes out of translation.
事实上,就胰岛素而言,翻译完成后的形式,还不是蛋白质的最终形式
Well, insulin is a protein, it's produced by cells in the pancreas, it circulates in your blood.
胰岛素是一种蛋白质,由胰腺细胞分泌,随着血液不断在体内循环
An alternate way is to go to the cell that's making the protein that you want.
另一种方法是,找到制造你想要的蛋白质的细胞
It's a protein that's produced by other cells in the body and when it's enriched in a certain area it stimulates more production of red blood cells.
这种蛋白由体内的另一种细胞生成,而当其在某处富集时,就会刺激红细胞生成
The one that's on the top here is called ligand-gated ion channel and an ion channel is a protein that sits in the surface of a cell.
最上面的这个叫作配体门控离子通道,离子通道是一类位于细胞表面的蛋白
Often the state of a protein depends on whether it's phosphorylated or not.
蛋白的状态通常取决于,它们是否被磷酸化
But that's not all, that protein insulin is made in the form of a long polypeptide that not - that's not always the final version of the protein.
但这还没完,这个胰岛素蛋白刚翻译完成时,还是一段长多肽的形式,还不是蛋白质的最终形式
So, a protein that has tyrosine and it has tyrosine in a position such that it's on the outside of the protein and accessible to chemical reaction can be phosphorylated.
所以,一种蛋白质中含有酪氨酸,并且该酪氨酸位于,像蛋白质的外侧这样的位置,这样才能够发生磷酸化反应
For now, just picture it in this simple way as a molecule, usually a protein, that's embedded in the cell membrane and many receptors have a part of them that is extracellular.
现在,我只把这种分子图示出来,受体通常是一种蛋白质,它们镶嵌在细胞膜上,很多受体还有部分结构露在细胞外
I'll use that one as the example because it's a familiar one to most people and you know that the protein insulin is made only in your pancreas and certain cells of the pancreas.
我把它作为例子,是因为大多数人都很熟悉它,胰岛素只在胰腺中进行合成,某些胰腺细胞能够合成胰岛素
These are two examples I just gave you of introducing genes that affect the life of a cell, either by making it express a protein that it's not making properly that's important to its life, or by intentionally killing a cell by having it express a fatal gene.
刚才我所举两个例子,都只是影响单一细胞生命过程的,无论是使无法正常表达的重要蛋白,正常表达也好,或是有意地,导入致命的基因杀死细胞也好
DNA goes to RNA, goes to protein, that's it, and that is the way it happens in simple organisms like bacteria.
NA转录成RNA接着翻译成蛋白质,仅此而已,而这仅是细菌那样的简单有机体中的机制
Those regions that are not are spliced out during RNA processing to form the mRNA transcript that's used to make the protein.
而这些与生成胰岛素无关的区域,在RNA剪接过程中就被剔除,从而生成转录蛋白质的mRNA
If it's making the protein you want, it must be producing messenger RNA with that gene on it.
如果它正在制造你想要的蛋白质,它一定也在制造,你要的基因的mRNA
That's making the cell look foreign because some of that foreign protein is on the surface with MHC1.
这使得整个细胞亦被视为外源物,因为某些外源蛋白,和MHC1共同出现在细胞表面
It's more complicated in making protein from an RNA strand and that complication is called the genetic code.
而从一条单链RNA翻译为蛋白,这个过程更为复杂,称之为遗传密码
It's called the G-protein coupled receptor because it's a receptor, like the one shown here, that's coupled to a special molecule called a G-protein.
之所以叫这个名字是因为这种受体,就像这里展示的一样,是与一种叫做G蛋白的特殊分子偶联的
I don't want to go through this in detail because I assume that you know it, plus I think it's a little bit easier to read and have some time to digest, but this process of translation or conversion of messenger RNA into a protein is a complicated biological process that's occurring all the time.
我不想在这些上讲太多的细节,因为我猜你们之前都有所了解了,你们花上一点时间,就能消化这些内容,但mRNA翻译,或者说转译成蛋白质的过程,是个极其复杂的生物过程,而且每时每刻都在发生
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