What's new in theory is the element of skepticism that literary criticism by and large which is usually affirming a canon of some sort doesn't reflect.

这新内容就是怀疑主义元素,它是文学评论,所不具备的,文学评论总是坚持某种原则。

耶鲁公开课 - 文学理论导论课程节选

And so, by and large, until this freon was invented by Midgley, there wasn't a good gas that had the right properties to be used for a refrigerant.

因此，总的说来，直到Midgley发明氟利昂，没有一个气体,能被很好的用作制冷剂。

麻省理工公开课 - 固态化学导论课程节选