But Masha Lipman from the Carnegie Endowment for International Peace in Moscow says she does not expect the protests will lead to significant changes in the Kremlin.

VOA: standard.2010.06.10

Or people like Richie Davidson actually scanned the brain and showed significant changes as a result of an 8-week meditation program.

或像是Richie，Davidson，通过扫描大脑,显示八周的冥想项目,可以产生重要改变。

哈佛公开课 - 幸福课课程节选

And although U.S.officials say small adjustments may be possible in the specific plan for an air base in northern Okinawa, Secretary Gates said he doubts the U.S.Congress would agree to significant changes in the agreement, particularly if they would cost the United States more money.

VOA: standard.2009.10.20