"I don't see a need to overhaul the regulations. The regulations cover the major causes of pipeline failures,and we do not see any gaps."

VOA: special.2011.07.08

Coronary artery disease is one of the major causes of death in western countries.

冠状动脉疾病,是西方国家主要致死性疾病之一

耶鲁公开课 - 生物医学工程探索课程节选

"That is why we are asking for mitigation. The developed world yes you are the major causes.

VOA: standard.2009.10.13

And without a vaccine, Dr.Fauci says the best methods of prevention are these: encourage people to limit the numbers of sexual partners encourage men to use condoms train more doctors to perform adult male circumcision empower women to choose their sex partners and protect themselves from getting the virus that causes AIDS All of these goals still remain major challenges.

VOA: standard.2010.07.17