CYP2C9 gene has several mutant alleles leading to genetic polymorphisms in humans.
CYP2C9基因具有遗传多态性，在人类存在几种等位基因的突变体。
The CYP1B1 which function as the susceptible genes to breast cancer has many genetic polymorphisms.
该基因存在遗传多态性，目前已对CYP1B1基因多态性与乳腺癌易感性进行了多项研究。
It has been reported that GSTM1, GSTT1 genetic polymorphisms are associated with several malignancies.
据报道，GSTM1、GSTT1基因多态性与多种恶性肿瘤的发生密切相关。
Further studies should be needed on the association between the genetic polymorphisms in GSTP1 and the risk of BP.
GSTP1基因多态与慢性苯中毒遗传易感性的关系仍需进一步研究。
Objective: to investigate the correlation between XRCC1 genetic polymorphisms and susceptibility to human lung cancer.
目的：探讨XRCC1基因单核苷酸多态性与肺癌易感性的关系。
Objective To explore the association between genetic polymorphisms of XRCC1 and susceptibility to acute childhood leukemia.
目的探讨XRCC1基因多态与儿童急性白血病遗传易感性的关系。
The genetic polymorphisms due to mutations in the methylene tetrahydrofolate reductase gene may increase the risk for NTDs.
亚甲基四氢叶酸还原酶基因突变导致的遗传多态现象可增加神经管缺陷(ntd)发生的危险性。
To study the relationship between essential elements and GST genetic polymorphisms in patients with chronic benzene poisoning.
探讨谷胱甘肽硫转移酶（GST）基因多态与慢性苯中毒患者血清中必需元素的关系。
Objective To determine the association of N-acetyltransferases 2(NAT2)genetic polymorphisms and the susceptibility to stomach cancer.
目的探讨N-乙酰转移酶2（NAT2）基因多态性与胃癌易感性的关系。
Methods CYP1A1 and GSTM1 genetic polymorphisms were determined by PCR-RFLP in 163 lung cancer cases and healthy controls respectively.
方法用PCR-RFLP技术分析了原发性肺癌组和住院对照组（各163例）的CYP1A1、GSTM1基因的多态性、基因型分布频率和交互作用。
Conclusion The genetic polymorphisms of ALDH2 might contribute to gastric cancer susceptibility and interact with environmental exposure.
结论ALDH2基因多态性与胃癌易感性有关，并与环境暴露有一定的交互作用。
[Objective] To study the relationship between essential elements and GST genetic polymorphisms in patients with chronic benzene poisoning.
[目的]探讨谷胱甘肽硫转移酶(GST)基因多态与慢性苯中毒患者血清中必需元素的关系。
Objective: To study the possible relationship between CYP1A1 genetic polymorphisms and susceptibility of acute lymphoblastic leukemia(ALL).
目的探讨CYP1A1基因多态性与急性淋巴细胞白血病（ALL）遗传易感性的关系。
Objective To explore the association between genetic polymorphisms of DNA repair genes XRCC1 , XRCC3 and susceptibility to chronic benzene poisoning.
目的探讨DNA修复基因XRCC1、XRCC3多态性与慢性苯中毒遗传易感性的关联及其与慢性苯中毒潜伏期的关系。
Methods Using multiple PCR and PCR-RFLP methods, we studied the NAT1 genotypes and its genetic polymorphisms of the peripheral blood samples from 140 Han people.
方法在140名汉族健康人的外周血中，应用聚合酶链反应（PCR）限制性片段长度多态性分析（RFLP）及多重PCR技术，进行NAT1等位基因分型研究。
Objective to examine the relationship of genetic polymorphisms of glutathione S-transferase (GST) including GSTM1 and GSTT1 and the susceptibility to childhood leukemia.
探讨谷胱甘肽s转移酶m 1 (GSTM1)和T1 (GSTT1)基因多态性与儿童白血病遗传易感性的关系。
The genetic polymorphisms of the DNA repair gene XRCC1 might contribute to the susceptibility to gastric cancer and interact with smoking, drinking, pickle, engorgement.
XRCC1基因多态性可能会增加胃癌的易感性，并可能与烟酒嗜好、腌制食品及暴饮暴食存在协同作用。
Objective To explore the association between genetic polymorphisms of glutathione S-transferase (GST) M1 and T1 and susceptibility to Kazak population esophageal cancer (EC).
目的为探讨与致癌物代谢有关的谷胱甘肽转硫酶（GST）T1和M1基因多型性与哈萨克族食管癌易感性的关系。
Several genetic polymorphisms of the aldosterone synthase gene (CYP11B2), which may influence the plasma aldosterone levels, had been reported to influence the blood glucose levels.
醛固酮合成酶基因(CYP11B2)部分位点的多态性改变除导致血浆醛固酮水平发生改变外，还与血糖变化密切相关。
Objective To study the relationship of genetic polymorphisms of cytochrome P4502E1(CYP2E1) and glutathione S-transferase M1(GSTM1) with genetic susceptibility of aplastic anemia(AA).
目的探讨CYP2E1和GSTM1基因多态性与再生障碍性贫血（简称再障）遗传易感性的关系。
Studies demonstrated that there is a wide variation of genetic polymorphisms of genes, which could be genetic factor of different susceptibility to diseases among different ethnic groups.
研究表明，不同种族之间遗传基因序列存在差异，可能是疾病易感性不同的遗传基础。
Until recently, the most important genetic risk factor for AD was the presence of the allele E4 of the apolipoprotein e, but recently other genetic polymorphisms of risks have been identified.
直至最近，AD最重要的遗传易感基因，载脂蛋白e- e4的等位基因才被发现，但是其他基因遗传多态性也被发现。
The aim of this study is to investigate the relationship between genetic polymorphisms of MTHFR C677T or A1298C and the response to platinum-based chemotherapy in non-small cell lung cancer (NSCLC).
本研究旨在观察mthfr基因C677T、A 1298c多态与非小细胞肺癌(NSCLC)患者对铂类药物为基础的化疗方案敏感性的关系。
Since the HLA system is one of the most complex human genetic polymorphisms, its application in forensic medicine included disputed paternity and criminal identification, have been fairly recognized.
HLA是迄今人类最复杂的遗传多态性系统，其在法医学上的应用，包括亲子鉴定和个人识别的重要性日益被认识。
Conclusions genetic polymorphisms in EPHX1 may be associated with the risk of CBP, and further research is needed for the association between genetic polymorphisms in EPHX2 and susceptibility to CBP.
结论EPHX1基因多态性可能与慢性苯中毒发生危险性相关，而EPHX2基因多态与慢性苯中毒易感性关系需进一步研究。
Current genetic tests analyze about 600,000 SNPs (single nucleotide polymorphisms) or 0.1 percent of the entire genome.
当前的基因检测分析了大约600,000个SNP(单核苷酸多态性)，只是整个基因组的千分之一。
ConclusionThe ARIX gene polymorphisms, especially the nucleotide change of G153A may be one of genetic risk factors for concomitant exotropia.
结论ARIX基因多态性，尤其是G153 A核苷酸突变可能是共同性外斜视的遗传风险因子。
To study the genetic marker polymorphisms and role of microsatellite of inbred strain mice.
目的研究近交系小鼠微卫星位点的遗传标记多态性及其意义。
As a codominant genetic marker, restriction fragment length polymorphisms, referred as RFLPs, has been widely Applied to the prenatal diagnosis of some genetic diseases.
限制性酶切片段长度多态性（RFLP）作为共显性的遗传标记，已广泛应用于遗传病的产前诊断。
Objective To study the HLA-DRB1/DQB1 allele polymorphisms and genetic characters of the children of Bai and Yi nationalities in Kuming.
目的研究昆明白族和彝族儿童HLA-DRB1／DQB1等位基因多态性，分析比较昆明白族和彝族人群的遗传特点。
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