劳斯肉瘤病毒包含触发肿瘤形成的src基因。
Rous sarcoma virus contains the src gene that triggers tumor formation.
但是,这种更新的技术需要利用病毒将基因转入皮肤细胞,这增加了发生肿瘤的风险。
But the newer technique involves putting genes into the skin cells using viruses, which also raises a risk of cancer.
研究者改造了这种病毒,增加了来自某个患者肿瘤细胞的特异抗体的基因。然后,他们使用携带这种基因的病毒感染烟草植物。
The researchers altered the virus, adding the specific antibody gene from a patient's cancer cells. Then, they infected the tobacco plants with the gene-carrying virus.
此外,同一类的增变基因酶起着低估的作用,在非淋巴肿瘤,抗病毒反应,并在后生重新编程。
Furthermore, the very same class of mutator enzymes plays an underappreciated role in non-lymphoid cancers, in antiviral responses and in epigenetic reprogramming.
结论:杆状病毒载体能够介导HHV - 8肿瘤转化基因k12编码的蛋白在昆虫细胞中表达。
Conclusion: Baculovirus transfer vector may mediate the coding protein of HHV-8 K12 gene expressed in insect cells.
结果:与野生型腺病毒相比,重组腺病毒能显著地提高目的基因在四种不同肿瘤细胞中的表达。
Results Fiber-mutant adenovirus vector showed a notably enhanced gene expression in four different tumor cells compared with that of conventional ones.
腺病毒作为新兴的载体因其转染效率和表达效率高而日益受到重视,成为肿瘤基因治疗的主要载体之一。
As the newly emerging vector, recombinant adenovirus is being given more attention and has become the major vector of gene therapy because of its high rate of transfection and expression.
病毒载体的靶向性问题是肿瘤基因治疗中的重要研究热点,靶向病毒载体是提高肿瘤基因治疗安全性和有效性的重要途径。
Vector tropism is a research hot spot in cancer gene therapy, and targeted viral vectors play a key role in the enhancement of safety and efficiency in cancer gene therapy.
目的研究新型非病毒载体磷酸钙纳米颗粒的生物学特性,评估其在肿瘤基因治疗中应用的前景。
ObjectiveTo study the biological characteristics of calcium phosphate nanoparticles and evaluate the promising in cancer gene therapy.
方法建立人卵巢癌裸鼠动物模型,检测腺病毒介导的人血管抑素基因对肿瘤生长的抑制作用。
Methods A human ovarian cancer model using a nude mice was built to test the suppressive effect of human angiostatin gene mediated by adenovirus on the tumor growth.
目前,NSC在恶性脑肿瘤中基因治疗的应用,主要包括构建载体和包装病毒载体。
At present, the applications of NSC gene therapy of malignant brain tumor mainly includes the construction of carriers and the package of viral vectors.
目的:构建含人IL -21基因的重组腺病毒表达载体,为IL - 21基因治疗肿瘤研究奠定基础。
Objective: to be as the foundation of the tumor therapy with targeting IL-21 gene by constructing of recombinant interleukin 21 gene adenovirus expression vector.
目的构建表达人类白细胞抗原- E (HLA - E)基因慢病毒载体,探讨慢病毒介导HLA - E基因在肿瘤免疫中的意义。
Objective to construct the lentiviral expression vector of HLA-E gene and investigate its significance for further study on tumor immunity.
目的研究结合基因治疗与病毒治疗双重优势的病毒-基因系统对肿瘤的治疗功效。
Objective to develop a novel vector system, which combines the advantages of the gene therapy and virus therapy, and to observe its therapeutic effect on lung cancer.
通过慢病毒整合位点鉴别,我们得以分辨转移和非转移瘤并明确可区分这两种不同类型肿瘤的基因表达改变。
Identification of the lentiviral integration sites allowed us to distinguish metastatic from non-metastatic tumours and determine the gene expression alterations that distinguish these tumour types.
他认为,肿瘤细胞,如果它们载有致癌病毒,应港湾病毒DNA整合到它们的基因组。
He assumed that the tumour cells, if they contained an oncogenic virus, should harbour viral DNA integrated into their genomes.
该新型溶瘤腺病毒突变体在基因治疗中具有良好的临床应用前景,可用于多种人体肿瘤的治疗。
This new oncolytic adenovirus mutant has good clinical prospect in gene curing so to used in curing many kinds of human tumors.
该新型溶瘤腺病毒突变体在基因治疗中具有良好的临床应用前景,可用于多种人体肿瘤的治疗。
This new oncolytic adenovirus mutant has good clinical prospect in gene curing so to used in curing many kinds of human tumors.
应用推荐