• X inactivation starts at the X-inactivation center(XIC) and spreads throughout the chromosomes.

    染色体开始X染色体失活中心XIC),然后传播到整条染色体。

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  • The genes that escape X inactivation have been recently found in human and in mouse.

    最近人和小鼠发现了逃避X失活基因

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  • Study on the mechanisms of 'escape' is helpful to the understanding of gene regulation by X inactivation.

    探讨这些基因逃避X失活机制有助于理解X染色体失活如何对基因表达进行调控的。

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  • The methylation of histone H3-K27 was proved to be linked to several silencing phenomena including homeotic-gene silencing, X inactivation and genomic imprinting.

    蛋白H3第27位赖氨酸甲基化同源基因沉默X染色体失活、基因印记等基因沉默现象有关;

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  • Because these genes are carried on the X-chromosome, they are subject to a process known as X-chromosome inactivation.

    由于这些基因存在于X染色体它们发生了X染色体失活处理

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  • X inactivation starts at the X inactivation center (XIC) and spreads throughout the chromosome.

    失活开始XIC,然后传播条染色体

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  • Objective To explore the relationship between X - linked spondyloepiphyseal dysplasia tarda (SEDL) gene escaping X chromosome inactivation( XCI) and SEDL phenotype.

    目的探讨X-连锁迟发性脊椎骨骺发育不良SEDL基因逃避X染色体失活XCI与临床表型的关系

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  • This phenomenon is mostly seen in imprinted genes and X-chromosome inactivation where DNA methylation of promoter regions leads to repression of gene expression.

    这种现象主要印迹基因X染色体失活区域看到,这些区域中的启动子区的DNA甲基化导致基因表达抑制

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  • To assess the clonal origin of renal clear cell carcinomas by the study of X-chromosome inactivation pattern in female clear cell renal carcinomas and normal renal tissues.

    实验将通过研究女性透明细胞正常肾组织X染色体活类型判断肾透明细胞癌克隆起源

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  • Objective to study the clonality of palmar fibromatosis by molecular genetic analysis of X chromosome inactivation pattern at a polymorphic site of human androgen receptor gene (HUMARA).

    目的通过雄激素受体(HUMARA)基因位点克隆分析技术确定纤维瘤病是否为肿瘤性增生。

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  • Objective to study the clonality of palmar fibromatosis by molecular genetic analysis of X chromosome inactivation pattern at a polymorphic site of human androgen receptor gene (HUMARA).

    目的通过雄激素受体(HUMARA)基因位点克隆分析技术确定纤维瘤病是否为肿瘤性增生。

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