Use of single-ligand formulations led to a reduction in viability (increased toxicity) not only in target KB cells but also in off-target cells with the targeted receptor available.
使用单配体配方不仅会导致靶向KB细胞活性的减少（增强了毒性），同时也使含有靶向受体的非靶向细胞活性降低。
Conclusion the toxicity of lead on neuron development might related to the change of trace element concentration, reduction of antioxidation ability and increasing apoptosis in brain.
结论铅的发育神经毒性与中枢神经系统铜等微量元素的改变、抗氧化能力下降及由此所致的细胞凋亡数量增加有关。
Selective targeting of drugs to kidneys may enable an increased renal effectiveness combined with a reduction of extrarenal toxicity.
将药物靶向到肾脏不仅能降低肾外毒性，而且能增加药物在肾脏的作用效果。
When boron content was higher, the content of proline was accumulated, which could activate the oxidative stress reaction, and result in reduction of boron toxicity in Huangguogan roots and leaves.
尤其当硼含量较高时，脯氨酸含量有所积累，激活氧化应激反应从而降低黄果柑根、叶的硼毒害作用。
Terms of toxicity, GP-based reduction in the number of platelet, TP group reduce the number of white blood cells mainly were in the tolerable range.
毒副反应方面，GP组血小板数目减少为主，TP组白细胞数目减少为主，均在可耐受的范围内。
Combination is the soul of formulae. In general, compatibility in compound formulae aims at synergy and reduction of toxicity.
配伍是方剂的灵魂，复方中的配伍组合从总体上都实现了趋利避害，从而确保方剂增效减毒的总体目标。
Combination is the soul of formulae. In general, compatibility in compound formulae aims at synergy and reduction of toxicity.
配伍是方剂的灵魂，复方中的配伍组合从总体上都实现了趋利避害，从而确保方剂增效减毒的总体目标。
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