The next part of dissertation is to design ligand for specific target proteins.
论文的第二部分是进行两类实际蛋白质的抑制剂设计。
Similar drugs often share target proteins, modes of action and unpleasant side effects.
同种药药物通常作用于同一蛋白质，有同样的作用模式和同样的副作用。
The target proteins were released from the cells by sonication and further purified with GST column.
经超声波破碎菌体释放目蛋白，并用GST亲和层析进一步纯化得到目的蛋白。
Using gene fusion technology, polypeptide fusion tags can be engineered into target proteins at the genetic level.
多肽融合标签能够赋予目标蛋白新的特性，便于目标蛋白的定位、追踪、纯化以及结构和相互作用研究。
To obtain human protein tyrosine phosphatase type 4A2 (PTP4A2) gene expressed in E. coli and purify the target proteins.
获取人蛋白酪氨酸磷酸酯酶4A2（PTP4A2）基因并高效表达纯化，对于产物的体外活性进行测定。
The addition of protease inhibitors to the cell lysis buffer AIDS in the preservation of target proteins in the cell extract.
向细胞裂解液中加入蛋白酶抑制剂后可以保护细胞提取物中的靶蛋白。
In order to study the phosphorylation status of specific target proteins the phosphorylated residue of interest must remain intact.
为了研究特异靶蛋白的磷酸化状态，磷酸化的残基必须保持完整。
In order to study specific target proteins of interest protease-mediated degradation during the generation of protein lysates is to be avoided.
为了研究特异靶蛋白，必须防止蛋白酶介导的蛋白发生降解。
Many cancer therapeutics, such as EGFR inhibitors, target proteins that are kinases-enzymes that initiate a cascade of signals that tell cells to reproduce.
许多癌症治疗方法，如egfr抑制因子，靶向激酶-酶蛋白，而这些蛋白能启动新号级联反应而使细胞繁殖。
A hallmark of signal transduction pathways is the reversible phosphorylation of serine and threonine residues within specific sequences, or motifs, in target proteins.
目标蛋白特定序列和基序的可逆丝氨酸和苏氨酸残基磷酸化是信号转导通路的标志。
Since these modifications usually happen on lysine residues of target proteins, we assumed that the functions of IRF7 could be highly affected by the mutation of lysine residues.
IRF7的活性可能受到乙酰化、泛素化和类泛素化修饰的调控，而这些修饰一般都发生在赖氨酸残基，我们猜测，赖氨酸残基在IRF7的修饰过程中可能具有重要的作用。
Protein kinases are enzymes that turn other proteins on or off. The IKKE protein kinase appears to target proteins which, in turn, control genes that regulate the mouse metabolism.
蛋白激酶是一种可以控制其他蛋白开或是关的酶，IKKE蛋白激酶看起来是作用于调控小鼠代谢的基因的。
The face of HIV virus, the antibody can block the infection will be highlighted in the HIV surface protein as the capture target proteins from the virus membrane as the spines grow.
面对HIV病毒，能够阻断感染的抗体将突出在病毒表面的蛋白作为捕捉目标，这些蛋白就如同从病毒膜内长出的尖刺。
Objective To screen specific target proteins for early diagnosis or therapy of echinococcosis by screening the authoritative databases from all over the word with bioinformatics method.
孙俊锋，棘怀庆，雄英，李宗吉，王娅娜，赵巍【摘要】目的用生物信息学方法从世界权威数据库检索筛选能用于诊断或治疗的细粒棘球蚴靶蛋白。
The primary target of INH is the proteins involved in the biosynthesis of the mycolic acids.
INH的主要目标是参与霉菌酸生物合成的蛋白质。
Both tasocitinib and Incyte's drug, INCB028050, target Janus kinases, which mediate signalling by immune-system proteins called cytokines.
无论是tasocitinib还是Incyte的药物，INCB 028050，都是目标直指激酶，通过一种叫做细胞因子的免疫系统蛋白介导信号。
We could target specific abnormal proteins, put a polar charge on the nanoparticles and use magnets to focus them on those areas of the tumor.
我们可以针对不正常的蛋白质，在纳米粒中放上一个极性电荷，用磁力把它们集中到肿瘤部位。
Neurodegenerative diseases like Alzheimer's have long been associated with clumps of garbage proteins that researchers have tried to target with drugs for years.
类似alzheimer的神经组织退化疾病就被认为与簇状垃圾蛋白质的长期堆积有关。这些簇状垃圾蛋白质是研究学者们多年来利用药物攻击的目标。
It is important to know exactly how viral proteins are structured so that drug developers can target weaknesses within it, and therefore devise better treatments for people.
这项研究的重要性在于可以准确了解病毒蛋白的结构，将其薄弱处作为治疗靶点，进而开发出更好的治疗方法。
Nanobiomaterials can be widely used in the fields of monitoring and therapy of cancer, separation of cells or proteins, genic therapy, drug target delivery and release, and so forth.
纳米微粒在癌症的监测、治疗，细胞和蛋白质的分离，基因治疗，靶向和缓释控药物等中都有着广泛的应用。
Structurally familiar proteins should evade attack from the immune system while on their way to target cells.
熟悉蛋白质在结构上应回避攻击的免疫系统，而就其方法的靶细胞。
The expressed target protein accumulated up to about 15% and 10% of the total cellular proteins, respectively.
在大肠杆菌中表达量约占细菌总蛋白15 % ，在昆虫细胞中表达量约占细胞总蛋白10 % 。
In host-parasite diseases like Tuberculosis, non-homologous proteins as drug target are first preference.
在宿主-寄生虫疾病中，像结核病，非同源蛋白质作为药物靶点是首选。
Depend on the role of proteins, target cells were stimulated differentiation by an autocrine or paracrine manner to promote osteogenesis.
依靠蛋白质的作用，靶细胞被刺激分化，通过自分泌或旁分泌的方式促进成骨。
One embodiment of these binding proteins has one or more binding sites where each binding site binds with a target antigen or an epitope on a target antigen.
这些结合蛋白的一个实施方案含有一个或多个结合位点，其中每个结合位点与靶抗原或靶抗原上的表位结合。
METHODS: We analyzed the gene sequences and protein structures of BMP-1 and its related proteins, and chose a highly conserved fragment as target gene.
方法：通过分析BMP - 1类各种分子的基因序列及蛋白结构，选择其中的一个片段作为目的基因。
Insect GABA receptor is a target for pesticides and it is instructive to study the structure of insert GABA receptor proteins to develop efficient low-toxicity pesticides.
昆虫GABA受体是农药的作用靶标，研究昆虫GABA受体蛋白的结构对开发高效低毒的农药具有重要的指导意义。
Insect GABA receptor is a target for pesticides and it is instructive to study the structure of insert GABA receptor proteins to develop efficient low-toxicity pesticides.
昆虫GABA受体是农药的作用靶标，研究昆虫GABA受体蛋白的结构对开发高效低毒的农药具有重要的指导意义。
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