AIM To study on the alterations of t suppressor cell function in patients with ulcerative colitis (UC) and Crohn's disease (CD) and their clinical significance.
目的研究溃疡性结肠炎(UC)和克隆病(CD)患者T抑制细胞的活性及其临床意义。
Objective To explore the changes of CD8 + t cell subtypes especially CD8 + CD28 -t suppressor cells in rats with experimental colitis induced by 2, 4-dinitrofluorobenzene (DNFB).
目的探讨CD 8 +T细胞亚群尤其是CD 8 + CD2 8 - T抑制细胞在2,4二硝基氟苯(DNFB)大鼠实验性结肠炎模型中的变化及其可能作用。
In addition to the suppressor cell dysfunction the distribution of T lymphocyte subsets is also abnormal and the OKT_4/OKT_8 ratio is significantly decreased in patients with HBV infection.
此外还证实HBV感染患者抑制性T细胞在功能和表型上的不一致，即抑制性T细胞功能低下而OKT_8的抑制性T细胞百分率增高。
In addition to the suppressor cell dysfunction the distribution of T lymphocyte subsets is also abnormal and the OKT_4/OKT_8 ratio is significantly decreased in patients with HBV infection.
此外还证实HBV感染患者抑制性T细胞在功能和表型上的不一致，即抑制性T细胞功能低下而OKT_8的抑制性T细胞百分率增高。
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