To assess the immunogenecity and efficacy of the yeast recombinant hepatitis B vaccine (YHB vaccine) for the prevention of hepatitis B in the newborns.
评价接种酵母重组乙肝疫苗（基因疫苗）的免疫效果与免疫持久性，为基因疫苗的推广应用及高危新生儿乙型肝炎的预防提供依据。
Objective To investigate the effects of anti-HBV specific active immunotherapy on non-responsive persons immunized with standard recombinant hepatitis B vaccine.
目的探讨抗HBV特异性主动免疫疗法对标准重组乙型肝炎（乙肝）疫苗无应答者的免疫效果。
Objective:To investigate the antibody response to hepatitis B vaccination and the necessity of reinforcement of recombinant hepatitis B vaccine (RHBV) at 12 month.
目的：探讨重组酵母乙肝疫苗新生儿接种后抗体应答持续时间，强化复种的必要性。
Objective:To investigate the antibody response to hepatitis B vaccination and the necessity of reinforcement of recombinant hepatitis B vaccine (RHBV) at 12 month.
目的：探讨重组酵母乙肝疫苗新生儿接种后抗体应答持续时间，强化复种的必要性。
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