Objectives: Grapefruit juice is responsible for drug interactions mediated by intestinal cytochrome P4503A4 inhibition and possibly P-glycoprotein inhibition in enterocytes.
目的:葡萄柚汁通过对小肠细胞色素P4503A4和潜在性对肠上皮细胞P-糖蛋白的抑制作用,进而影响药物代谢。
Objectives: Grapefruit juice is responsible for drug interactions mediated by intestinal cytochrome P4503A4 inhibition and possibly P-glycoprotein inhibition in enterocytes.
目的:葡萄柚汁通过对小肠细胞色素P4503A4和潜在性对肠上皮细胞P-糖蛋白的抑制作用,进而影响药物代谢。
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