Objective: P53 gene involves in cell cycle regulation.
目的：p 53基因参与细胞周期调控。
Cancer cells died following 24 hour DADS treatment that activated the p53 gene.
24小时的DADS治疗，激活p 53基因导致癌细胞死亡。
When they saw a promising signal for PL, they assumed it worked by enhancing the p53 gene.
他们在看到PL产生的很有希望的信号时，以为这种物质是通过促进p53基因发挥作用的。
Objective To observe the relationship between P53 gene mutation and malignant eyelid tumor.
目的探讨P 53基因突变与眼睑恶性肿瘤发生的关系。
P53 gene is the most prominent tumor suppressor gene in human cancer among those genes that have been found till now.
p 5 3基因是至今为止发现的与人类肿瘤相关性最高的基因。
Results: The expression of P53 gene in hepatoid adenocarcinoma of stomach was higher than other types of gastric carcinoma.
结果：胃肝样腺癌P53基因表达明显高于其它类型胃癌。
It was concluded that PCR SSCP silver staining method for the detection of P53 gene mutation is quick reliable and practical.
结论：PCRSSCP银染色法是一种可靠、快速、实用的P 53基因突变检测方法。
The protein(P53) encoded by mutant p53 gene (mtp53) not only losses these functions, but also make cell malignant transformation.
突变型p53基因的编码蛋白不但丧失上述功能，甚至出现了促使细胞癌变的作用。
The P53 gene mutation site in osteosarcoma was mostly in GC sequence of exon, especially in exon 7, which was different with other tumors.
骨肉瘤p 53基因多位于外显子GC序列，尤其是外显子7，有别于其他肿瘤好发位点。
The results suggested that mutation of the P53 gene may be still as an independent prognostic factor in the gastric cancers with serosa invasion.
这些结果提示：P 53基因突变可能浆膜浸润胃癌病人预后的一个重要的非依赖性因子。
RESULTS: the inhibition rates of majority antitumor drugs in the P53 gene normal group were significantly higher than in the P53 gene abnormal group.
结果：统计比较抗癌药在P53基因正常组和P 53基因异常组中的抑制率，发现多数抗癌药抑制率前者显著地大于后者。
In the latest study, the scientists used a genetic trick to make zebrafish turn green when the p53 gene was switched on to explore the way it was regulated.
在最近的研究中，科学家利用一种基因技巧使在p 53基因打开的时候，让斑马鱼变成绿色，来探索这种基因的调节方式。
Objective: To analyse the significance and relationship between p53 gene mutation and the expression of mutant type p53 gene protein in the laryngeal carcinomas.
目的：探讨喉癌P53基因突变与突变性P 53基因蛋白表达之间的相互关系及意义。
Lesley Walker, cancer Research UK's director of cancer information, said: "This is a really exciting study which improves our understanding of how the p53 gene works."
癌症研究团队英国方面的癌症信息主任莱斯利·沃克说，“这是一项激动人心的研究，增进了我们对于p53基因机理的了解。揭示它是怎样起调节作用的，对研发更有效的药品和癌症诊断方法有重要的意义。”
They found that the p53 gene makes not only the well-established p53 protein, but also an alternative "control switch" variation of the p53 protein - known as an isoform.
他们发现p53基因不仅产生大家熟知的p53蛋白质，同时还产生一种p53蛋白质变换“控制开关”的变种——对碘氧基苯甲醚。
The detection of P53 gene mutation plays an important role in predicting the malignant progression of bladder cancer and in early detection of bladder cancer recurrence.
P 53基因突变的检测对预测膀胱癌的进展，复发的早期诊断具有重要的临床意义。
Methods:Immunohistochemistry and PCR-SSCP were used to detect the expression of P53 protein and p53 gene mutation in 32 cases of TSCC and 10 cases of tongue leukoplakia.
方法：应用免疫组织化学和聚合酶链反应—单链构象多态性分析（PCR-SSCP）检测10例舌白斑和32例舌癌，并结合临床资料进行分析。
Normally zebrafish, which carry the same p53 gene as humans, can survive low doses of radiation, which causes damage to the DNA, because the gene steps in to repair that damage.
在通常情况下，像人类一样携带相同p 53基因的斑马鱼可以承受小剂量的放射，放射会对DNA造成损坏，而基因会加入对损坏的修复。
One of them will be able to distinguish about 20 different subtypes of leukaemia, and a second will be able to pinpoint mutations in the p53 gene, which can affect a cancer patient's prognosis.
其中一种能够辨别20种不同的白血病亚型，而另一种能够分辨出p53基因的关键变异，而这种基因能够影响癌症的预后。
Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.
一些小鼠还有肿瘤抑制基因p 53缺陷，这种缺陷突变存在与大约一半的人类肺癌。
They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.
他们发现当用DADS治疗时，有名的肿瘤抑制基因p53阻止了细胞循环 。
In 2005, researchers at Sloan-Kettering reported that the gene could stop massive tumor growth in prostate cancer even when another tumor suppressor, known as P53, was turned off.
早在2005年，斯隆·凯特琳中心的研究人员就曾报道了在另一种叫做P 53的肿瘤抑制基因关闭时，该基因甚至仍然可以阻止前列腺癌大肿瘤生长。
As Thompson began to study the gene, he found that it was a target for a tumor suppressor gene called p53, which is a major controller of cell activity in prostate and other cancers.
当Thompson开始研究这个基因时，他发现RTVP - 1基因是肿瘤抑制基因p53的靶基因，p 53是前列腺癌及其他癌症细胞活性的最主要控制者。
The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogene expression, DNA synthesis and repair systems, and cell apoptosis.
抑癌基因p53编码转录因子p53蛋白在调控癌基因表达、dna合成和损伤修复以及细胞凋亡中起关键作用。
In the nucleus prohibitins interact with transcription factors such as Rb and p53 to regulate target gene transcription (2, 5).
细胞核中，抑制素通过与转录因子如rb和p 53相互作用来调节靶基因的转录(2,5)。
In 2005, researchers at Sloan-Kettering reported that the gene could stop massie tumor growth in prostate cancer een when another tumor suppressor, known as P53, was turned off.
早在2005年，斯隆·凯特琳中心的研究人员就曾报道了在另一种叫做P 53的肿瘤抑制基因关闭时，该基因甚至仍然可以阻止前列腺癌大肿瘤生长。
WIP1 was initially identified as a p53 target gene, induced in response to ionizing radiation (1).
WIP1最初被认为是电离辐射应激后p 53的靶基因(1)。
Pathology: p53 tumor suppressor gene mutation, loss of heterozygosity (LOH) at 11p15 locus. PAX-FKHR gene fusion.
病理学：p53肿瘤抑制基因突变，第11p15基因座杂和性丢失。
Pathology: p53 tumor suppressor gene mutation, loss of heterozygosity (LOH) at 11p15 locus. PAX-FKHR gene fusion.
病理学：p53肿瘤抑制基因突变，第11p15基因座杂和性丢失。
应用推荐