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P450

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  • Cytochrome P450 is one of the most versatile enzymes in nature.

    细胞色素P 450酶自然界万能生物酶之一。

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  • Cytochrome P450 enzyme are an important enzyme family in drug metabolism.

    色素氧化酶p 450药物代谢中的一个重要酶系

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  • Objective:To study activity of cytochrome P450 for human liver microsomes.

    目的:为测定细胞微粒体细胞色素P450氧化酶活性

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  • They also bind tightly to some of the TB P450 enzymes and inactivate them.

    氮杂茂可结核菌内一些P 450酶类紧密结合使其失活。

    dj.iciba.com

  • The results showed that P450 (SCC) was located in the mouse ovary of 15-day pregnancy;

    研究发现15日龄卵巢内存在P450SCC免疫染色;

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  • The progress on the relationship between cytochrome P450 and drug-induced liver injury was reviewed.

    主要介绍细胞色素P450药物损伤的相关研究进展。

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  • Cytochrome P450 3a (CYP3A) is one of the key isoenzymes involved in the metabolism of clinical drugs.

    细胞色素P 4503A (CYP3A)参与临床药物代谢主要CYP同工酶之一

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  • OBJECTIVE to introduce the research status of cytochrome P450 and its new applications in clinical pharmacy.

    目的介绍细胞色素P 450研究进展及其临床药学工作实践中的指导意义。

    kns50.chkd.cnki.net

  • Unlike other P450s, P450nor has no monooxygenase activity although it belongs to the P450 super family (CYP55A).

    虽然属于P450超家族,但没有加单氧酶活性

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  • Objective To determine the distribution of cytochrome P450 1A1(CYP1A1) gene polymorphisms in Guangdong Hans women.

    目的探讨广东汉族妇女细胞色素P45 01A1CYP1A1基因多态性分布规律。

    dict.cnki.net

  • An example of a flavoprotein undergoing a one-electron transfer is with the microsomal NADPH-cytochrome P450 reductase.

    经历一个单电子转移黄素蛋白的例子微粒NADPH-细胞色素P 450还原酶。

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  • For many years, researches on Cytochrome P450 had been focused on their roles in exogenous drugs and poisons metabolism.

    多年来,细胞色素酶P 4 5 0的研究主要集中代谢外源性药物毒物的方面。

    dict.cnki.net

  • Aging related changes have been evaluated in hepatic cytochrome P450 content in rats by specific cytochrome P450 enzymes.

    大鼠细胞色素P 450含量年龄相关变化特异的细胞色素P 450酶引起的。

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  • Object; To explore the influence on liver cytochromes P450 by co- administration of piperine and glycyrrhizic acid in rat.

    目的研究胡椒配伍甘草使用对大鼠细胞色素P450影响

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  • Conclusion The K39 in HO has important effects on accepting and transporting electrons from NADPH-cytochrome P450 reductase.

    结论HO的碱性氨基酸K39在接受传递NADPH-细胞色素P450所提供的电子具有重要作用

    dict.cnki.net

  • Cytochrome P450 and GST are two important complex gene families of enzymes that metabolize therapeutic drugs and carcinogens.

    细胞色素P 450和谷胱甘肽s转移于抗肿瘤药物致癌剂代谢重要酶系。

    dict.cnki.net

  • In conclusion, levofloxacin significantly inhibited metabolism of metoprolol in the cytochrome P450 of rat hepatic microsomes.

    结论:左氧氟沙星抑制大鼠肝微粒体细胞色素P 45 0系统美托洛尔代谢

    dict.cnki.net

  • Study in Electrochemistry of Cytochrome P450 is a Profile of the effort in order to use Cytochrome P450 as catalyst in industry.

    细胞色素P 450电化学研究一个侧面反映了使细胞色素P 450达到工业催化剂的最终目的人们所作的不懈努力

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  • Cytochrome P450 (CYP450) is the crucial metabolizing enzymes in the bodies. It is the most important effect for drug metabolization.

    细胞色素P 450 (CYP450)机体药物代谢关键,在药物生物转化中起着重要作用

    www.fabiao.net

  • The present drug2013drug interaction can be attributed to a strong inhibitory effect on cytochrome P450-3A4 activity by voriconazole.

    究其原因,是因为伏立康唑细胞色素P450-3A4活性强大的抑制作用

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  • In recent years, researches found that there were many kinds of cytochrome P450 enzymes which related to multidrug resistance of tumor.

    目前研究发现细胞色素P 450与肿瘤多药耐药的发生密切相关。

    kns50.chkd.cnki.net

  • AIM: to investigate the interventional effect of cytochrome P450-CYP2J3 gene on hypertension and insulin resistance induced by fructose.

    目的观察细胞色素P 450 -CYP2J3基因果糖诱导高血压胰岛素抵抗的干预作用。

    dict.cnki.net

  • Objective to introduce the research status of cytochrome P450 and its new applications in the study of toxicity and new drug evaluation.

    目的介绍细胞色素P 450研究进展及其毒理学药物评价方面的应用

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  • This review provides a better understanding of the cytochrome P450 system with a focus on those enzymes most involved in drug metabolism.

    这次综述提供了一个大多数药物代谢有关的重点的细胞色素P 450系统了解

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  • The current status of researches involving biosynthesis genes of flavonoids compounds and taxol, and the plant P450 genes were introduced.

    介绍黄酮类化合物紫杉醇生物合成基因植物p450基因研究现状

    dict.cnki.net

  • The results implied that the change of GAS modulated by the cytochrome P450 monooxygenase genes might influence the columnar growth habit.

    由此推断细胞色素P 450单加基因所调控的赤霉素gas变化影响苹果柱型性状表达。

    dict.cnki.net

  • Objective: to study the effects of trans-resveratrol and trans-piceid on liver weight, contents of microsomal protein and cytochrome P450.

    目的研究反式白藜芦醇及反式白藜芦醇苷大鼠质量、肝微粒蛋白质细胞色素P 450的影响。

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  • Epilepsy is a common disease in nervous system. Most antiepileptic drugs are metabolized by liver enzymes. such as cytochrome P450 enzyme.

    (癎)危害人类健康的常见神经系统疾病,临床常用抗(癎)药多通过细胞色素P450代谢

    d.wanfangdata.com.cn

  • Azole and triazole drugs are cytochrome P450 inhibitors widely used as fungal antibiotics and possessing potent antimycobacterial activity.

    三氮药物作为细胞色素P 450抑制剂广泛被作为真菌药物和抗微生物药物使用。

    med.essaystar.com

  • Objective: to investigate the effects of the ethyl acetate extract of Semen Hoveniae capsule on liver microsomal cytochrome P450 system in rats.

    目的观察枳煿子乙酸乙酯提取物胶囊大鼠微粒体细胞色素P 450及其同工酶影响

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