This review will focus on the physiology of the osteoclast .
本综述将着重讨论破骨细胞的生理。
The mature osteoclast cells themselves do not express the Flt-1 receptor.
成熟的破骨细胞本身并不表达Flt - 1受体。
Your body USES it in the process of making osteoclast and osteoblast cells.
你的身体用它制作破骨细胞和成骨细胞。
Its differentiation effect on inhibiting osteoclast was assessed with statistics analysis.
统计学分析评价其抑制破骨细胞分化效果。
The inhibition of the differentiation and maturity of osteoclast will inhibit bone resorption.
抑制破骨细胞的分化成熟就能有效控制骨的吸收。
Conclusions Osteoclast-mediated bone resorption was inhibited by the bisphosphonate administration.
结论双膦酸盐对破骨细胞性骨吸收有明显的抑制作用。
Here we show that these three factors have critical roles in osteoclast differentiation and function.
在此论文中阐述了这些因子对破骨细胞的分化和功能具有重要作用。
Purpose To study the clinicopathological features of mammary carcinoma with osteoclast-like giant cells.
目的：探讨伴破骨细胞样巨细胞乳腺癌的临床病理特点。
The TRAP staining was performed on the distal femur of the other side to detect the number of osteoclast.
取另一侧股骨远端行TRAP染色，观察大鼠股骨远端破骨细胞数量的变化。
Purpose To study the clinicopathological features of renal tumors with osteoclast-like giant cells (RT-OGC).
目的探讨伴破骨细胞样巨细胞肾肿瘤(RT OGC)的临床病理特点。
Results: Caseification, osteoclast hyperplasia and bone destruction were found in the location of Mt sonicate injection.
结果：观察显示，结核因子注射部位出现干酪性坏死，破骨细胞数量增加，骨质破坏明显。
Objective To investigate the effect of different osteotropic hormones on the formation of rat osteoclast like cell in vitro.
目的研究不同诱导因子对大鼠破骨细胞样细胞体外形成的影响。
The activity between the osteoblast and the osteoclast, with their mutual effects, influence the procedure of bone remodeling.
成骨细胞与破骨细胞间的活动及其相互作用共同影响着骨改建的过程。
Object: the study is to find a feasibility method of obtaining human osteoclast-like cells for the purpose of further research.
目的：探讨可行的获取人破骨细胞样细胞以供进一步研究的方法。
Interestingly, it appears that insulin signaling in osteoblasts induced osteocalcin activation by stimulating osteoclast activity.
有趣的是，似乎成骨细胞中的胰岛素信号通过刺激破骨细胞活性诱导骨钙素活性。
Mononucleated osteoclast reached peak level at 3 days after tooth movement, while multinucleated cells reached peak level at 5 days.
其中单核破骨细胞在第3天、多核破骨细胞在第5天时达到峰值。
Summary of Background Data. Osteopetrosis is characterized by osteoclast dysfunction, impaired bone resorption, and poor bone remodeling.
石骨症的特征是破骨细胞功能出现障碍，使骨吸收减慢，导致骨再建缺陷。
CONCLUSION: the inducing culture of osteoclast-like cells are gradually progressed, and the mechanisms have also been initially revealed.
结论：破骨样细胞的诱导培养已逐渐成熟，其具体机制得到初步揭示。
If the alveolar bone resorption can be controlled through inhibition of osteoclast, the anchorage teeth movement will be effectively managed.
如果能够控制破骨细胞的产生从而控制牙槽骨的吸收，就可以达到控制牙齿移动的目的。
What happens is that you take the medicine, the osteoclasts absorb it, and it poisons the osteoclast cells by cutting off their blood supply.
事情是这样的，当你吃了药，破骨细胞会吸收它“双磷酸盐”，然后“双磷酸盐”会切断破骨细胞的血液供应。
Results The trabecular bone volume and mean cortical thickness decreased in OVX, however, the number of osteoclast were higher than normal rats.
结果：去势大鼠骨组织皮质及骨小梁变薄，骨矿化率增高，矿化缘长度增加，小梁表面破骨细胞数明显增多。
Conclusions RAW264. 7 cell could be used as a preferable preoste-oclast model in respect of its osteoclast characteristic gene expression profile.
结论RAW264．7具有破骨细胞特征性基因表达谱，是一种较好的破骨前体细胞模型。
Moreover, Er-xian decoction obviously reduced osteoclast number(P<0.01)and enhanced bone density of femur metaphysis in ovariectomized rats(P<0.05).
减少破骨细胞数（P<0.01）且显著增加去卵巢大鼠股骨骨密度（P<0.05）。
Objective To determine whether leukotriene B4 (LTB4) could directly stimulate human osteoclast differentiation and activation independent of RANKL (ODF).
目的探讨白三烯（LT）B4能否不依赖细胞核因子资B受体激活剂配体（RANKL）直接促进人破骨细胞的分化和激活。
Determine the effect of BBC-containing serum on absorption of lacuna formed by oc in osteoblast and osteoclast co-culture system by toluidine blue staining.
运用甲苯胺蓝染色法观察含药血清对成骨细胞-破骨细胞共育体系中OC形成骨吸收陷窝的影响。
Conclusion on the resorbing surface of human deciduous teeth there are large amount of osteoclasts which can be used as a source of studying human osteoclast.
结论人滞留乳牙牙根吸收面存在大量的破骨细胞，是研究人破骨细胞的一个来源。
Objective to investigate the biological effects of platelet-derived growth factor (PDGF) -bb on the osteoclasts in the osteoblast-osteoclast co-culture system.
目的探讨血小板衍生生长因子(PDGF) -BB在成骨细胞-破骨细胞培养体系中对破骨细胞骨吸收功能的影响。
Postmenopausal osteoporosis is a kind of metabolic osteopathy, whose cause is that bone absorption of osteoclast is more forceful than osteogenesis of osteoblast.
绝经后骨质疏松症是一种代谢性骨疾病，是绝经后妇女雌激素水平降低导致破骨细胞的骨吸收大于成骨细胞的骨形成作用。
Postmenopausal osteoporosis is a kind of metabolic osteopathy, whose cause is that bone absorption of osteoclast is more forceful than osteogenesis of osteoblast.
绝经后骨质疏松症是一种代谢性骨疾病，是绝经后妇女雌激素水平降低导致破骨细胞的骨吸收大于成骨细胞的骨形成作用。
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