The causes for tubulointerstitial changes remain rather complex and the role of proteinuria in damaging nephridial tissue has been demonstrated by large number of clinical and experimental studies.
引起肾小管间质病变的原因比较复杂，其中蛋白尿的肾损伤作用已为大量临床和实验研究所证实。
The causes for tubulointerstitial changes remain rather complex and the role of proteinuria in damaging nephridial tissue has been demonstrated by large number of clinical and experimental studies.
引起肾小管间质病变的原因比较复杂，其中蛋白尿的肾损伤作用已为大量临床和实验研究所证实。
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