Objective To analyse the homology of mucin 1(MUC1) on mou se cells and human cells.
目的分析鼠与人粘蛋白1(MUC1)的同源性位点。
Objective to construct MUC1-targeted nanoparticles and evaluate its cytotoxicity in vitro.
目的构建MUC1靶向纳米粒,并在体外评估其抗肿瘤效应。
There was no relationship between the expression of MUC1 and the pathological types (P>0.05).
不同病理类型的乳腺癌组织中,MUC1表达无明显差异(P>0.05);
CONCLUSION: MUC1 gene immunization can significantly suppress H22 hepatocellular carcinoma growth.
结论:MUC1基因免疫显著抑制H 22肝癌生长。
The expression of nm23, MUC1 could be useful in judging the gastric mucinous carcinoma's prognosis.
MUC1的表达,对判断胃黏液癌的预后具有参考价值。
Objective: To study the expression of MUC1 and WT1 gene in acute leukemia and their clinical significance.
目的:探讨MUC1基因及WT 1基因在急性白血病的表达及临床意义。
Objective: To study the relationship between the gastric cancer and the expression of MUC1, MUC2 and MUC5AC in serum.
目的:检测胃癌患者血清中MUC1、MUC2及MUC5AC含量,探讨与胃癌的关系。
Purpose To study the expression of MUC1 and MUC2 and clinical pathological features in serous and mucinous ovarian tumors.
目的探讨卵巢浆液性和黏液性肿瘤中黏蛋白MUC1、MUC2的表达与临床病理特征的相关性。
Objective To investigate MUC1 and MUC5AC expression in specimens of pancreas fine-needle aspiration and evaluate the diagnostic value.
目的检测胰腺细针穿刺标本中粘蛋白MUC1、MUC5AC的临床意义。
Flow cytometric analysis of MCF-7 cells, using MUC1 (VU4H5) Mouse mAb (blue) compared to a nonspecifc negative control antibody (red).
使用MUC1 (VU4H5)鼠单抗(蓝色)对MCF-7细胞进行流式分析,对照使用阴性对照抗体(红色)。
Methods the immunohistochemical method (SP) was used to assay the expression of MUC1, MUC2 and MUC5AC in 40 large intestinal mucoid adenocarcinoma.
方法采用免疫组织化学法的SP法,检测40例大肠黏液腺癌组织中黏蛋白MUC1、MUC2和MUC5AC的表达。
Then in the animal model, it could form tumors in the normal C57BL/6 mice and immunohistological examination showed that this cell line could express MUC1 in vivo.
动物接种实验证实该细胞可在正常小鼠皮下成瘤,免疫组织化学检测可见该细胞系在C57BL/6小鼠皮下接种胰腺癌模型中可表达MUC1。
This article reviews the structure and function of MUC1 and some new research progress on the tumor metastasis related to MUC1, and explores its significance in tumor diag…
本文对MUC1的结构、功能及其在多种肿瘤转移中的研究进展进行了综述,并对其在肿瘤的临床诊断及治疗中的作用进行了展望。
Objective to determine the expression of MUC1 in regional lymph nodes from colorectal cancer to look for a reliable indicator in the detection of lymph node micrometastasis.
目的研究结直肠癌区域淋巴结中黏蛋白1 (MUC1)的表达,以寻找1种检测结直肠癌淋巴结微转移的可靠指标。
Conclusion T739 mouse bladder cancer cell lines and tumor-bear model expressing human MUC1 were successfully established for the development of tumor vaccines targeting MUC1.
结论建立稳定表达人MUC1T739小鼠膀胱癌细胞株和t739荷瘤小鼠模型,可用于肿瘤疫苗研究。
The aim of this study was to explore relationship between expression of mucin MUC1 and MUC2 in colorectal carcinoma and clinicopathological parameters and their clinical significance.
本研究的目的是探讨结肠直肠癌组织中粘蛋白MUC1和MUC2的表达与不同的临床病理参数间的关系及其临床意义。
The researchers tested transgenic mice that spontaneously develop IBD and then progress to colitis-associated colon cancer, producing the human version of MUC1 in both disease states.
研究者利用IBD自发转基因小鼠来进行试验,随后这些小鼠进展为肠炎相关性结肠癌,两种疾病均可产生异常增生的人类MUC1蛋白。
Since it is often overexpressed in many tumors and closely related to invasion, metastasis and prognosis of the malignancy, MUC1 might be exploited as a tumor marker for clinical application.
MUC1在肿瘤组织中异常表达,与肿瘤的侵袭、转移和预后密切相关,具有重要的临床应用价值。
To elucidate the expression of MUC1 core peptide in the human normal glandular epithelial cells, the MUC1 core protein was detected with BC1 antibody by means of immunohistochemical LAB method.
揭示MUC1粘蛋白核心肽在人正常腺上皮中的表达模式。用BC1抗体和LAB免疫组织化学方法检测组织中的MUC1核粘蛋白的表达。
Conclusion the prokaryotic expression vector of 8r-muc1 core peptide fusion protein has been constructed, and the fusion protein with biological activity has been successfully expressed and purified.
结论:构建了8r - MUC1核心肽融合蛋白原核表达载体并成功表达与纯化出具有生物学活性的融合蛋白。
Objective To detect the expressed level of Mucin gene (MUC1) in variety classes breast cancer, and approach this sense for the diagnosis of breast cancer, the metastasis and the prognostic evaluation.
目的检测MUC1基因在不同类型乳腺癌组织中的表达水平,探讨其在乳腺癌诊断、转移和预后评价中的意义。
Objective To detect the expressed level of Mucin gene (MUC1) in variety classes breast cancer, and approach this sense for the diagnosis of breast cancer, the metastasis and the prognostic evaluation.
目的检测MUC1基因在不同类型乳腺癌组织中的表达水平,探讨其在乳腺癌诊断、转移和预后评价中的意义。
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