MMP-2 is one of the main metalloproteinases active in neoplasia and is a marker of the malignant phenotype.
MMP - 2是肿瘤形成中的一种主要金属蛋白酶，可做为恶性表型的标记物。
The malignant phenotype of the cell line gradually disappeared while characteristics of mature cell were progressively increased.
癌细胞恶性表型逐渐消失，成熟细胞特征逐渐增多。
Objective To study the reverse effect on the malignant phenotype of human NPC cells CNE2 transfected with EBV-LMP1 antisense gene.
目的研究EB病毒LMP1反义基因对人鼻咽癌CNE2细胞恶性表型的逆转作用。
Conclusion: Overexpression of VEGF and CD31 is a marker of malignant phenotype of gliomas, which can be a supplement to histopathological diagnosis.
结论VEGF和CD 31在胶质瘤的高表达是胶质瘤恶性表型之一，可作为病理诊断的补充。
These data further demonstrated that NPC is a disease involving polygenic alteration and NAG12 gene could favor malignant phenotype reversion of NPC cells.
以上实验进一步说明鼻咽癌是多基因改变的疾病，NAG1 2的重表达有助于鼻咽癌恶性表型的逆转。
Conclusions: The overexpression of CD151 was correlated with malignant phenotype of intra hepatic cholangiocarcinoma and probably implicated in invasion and metastasis.
结论：肝内胆管细胞癌cd 151表达与其恶性表型相关，可能参与其侵袭和转移。
Conclusion the expression of APE1 is associated with the malignant phenotype of HCC. Overexpression and cytoplasm localization of APE1 can be used as a poorly prognostic marker for HCC.
结论APE1蛋白表达与HC C恶性表型有关，APE1蛋白过表达及细胞质表达的出现可能成为HCC预后不良的指标之一。
Conclusion ATP not only inhibits proliferation but also induces differentiation of a human gastric cancer cell line with reversion from malignant toward normal phenotype.
结论AT P不仅抑制人胃癌细胞的增殖，而且诱导分化，使人胃癌细胞的恶性表型向正常表型逆转。
CONCLUSION: Transfected CAR gene may enhance the adhesion ability of ovarian cancer SKOV3 cells, therefore, inhibit the malignant metastatic phenotype of SKOV3 cells.
结论：外源性CAR基因的导入可以增强卵巢癌细胞SKOV3间的粘附性，从而抑制肿瘤细胞的侵袭转移表型。
Significantly, the MSC-stimulated cancer cells do not acquire a stable metastatic phenotype; rather they revert to their pre-malignant state in the absence of contextual signals.
重要的是，受到MSC刺激的癌细胞并没有获得一个稳定的转移表现型，相反，它们会在没有背景信号的情况下回到其恶化前状态。
Significantly, the MSC-stimulated cancer cells do not acquire a stable metastatic phenotype; rather they revert to their pre-malignant state in the absence of contextual signals.
重要的是，受到MSC刺激的癌细胞并没有获得一个稳定的转移表现型，相反，它们会在没有背景信号的情况下回到其恶化前状态。
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