While we have not seen dose-limiting toxicity at this level with the slower infusion (without pre-medication), we have seen headache in two patients, which is a moderate adverse effect.
我们在慢速输液(没有前驱给药)的情况下还没有看到剂量限制性毒性，只看到两例患者出现头痛，是中等不良反应。
OBJECTIVE: to analyze the impact of infusion apparatus on the safety of clinical medication and to explore the precautionary measures to ensure clinical medication safety.
前言：目的：探讨输液器影响临床用药安全性的因素及预防措施，确保临床安全用药。
This seems to be reduced if we increase the infusion time, and it may respond to other medication given with the study drug? We are investigating this further.
如果延长输液时间，头痛会减少。或许它是和所研究药合用的其它药的不良反应呢？我们正在进一步研究。
METHODS: The factors influencing clinical medication safety induced by infusion apparatus were analyzed by reviewing of pertinent literature and simulating clinical trial.
方法：查阅相关文献，模拟临床试验，分析输液器影响临床用药安全性的各种因素。
Continuous pain medication infusion pumps developed.
发明持续止痛药物泵。
Continuous pain medication infusion pum developed.
发明持续止痛药物泵。
Continuous pain medication infusion pum developed.
发明持续止痛药物泵。
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