Objective To study the effect of Curcumine on Myleran-resistant HL-60 cells.
目的探讨姜黄素对马利兰耐药hl - 60细胞生长的影响。
NBT reduction test showed functional maturity of the differentiated HL-60 cells.
四唑氮蓝还原试验显示其功能亦渐超成熟。
Conclusion PR exerts effect on differentiation and induces apoptosis in HL-60 cells.
结论:普乐林具有诱导HL - 60细胞分化及凋亡的双重作用。
Results Nobiletin could significantly inhibit the proliferation of K562 and HL-60 cells in vitro.
结果诺必擂停对白血病细胞株k562、HL - 60的增殖有显著的抑制作用。
Objective:To study the effect of Ginkgo biloba exocarp polysaccharides(GBEP) on HL-60 cells in vitro.
目的:研究银杏外种皮多糖对体外HL-60细胞的作用。
Objective To investigate the telomerase activity in HL-60 cells treated by Astragalus Polysaccharide.
目的研究黄芪多糖对人早幼白血病h L - 60细胞端粒酶活性的作用。
The DNA agarose gel electrophoretic observations showed the DNA ladder pattern formation in HL-60 cells.
进而抽提了HL- 60细胞的DNA,进行琼脂糖凝胶电泳观察,显示出阶梯状条带形成的细胞凋亡特征。
Telomerase activity of HL-60 cells treated with wogonin in different concentrations was significantly inh...
不同浓度的汉黄芩素能下调HL - 60细胞的端粒酶活性,且同样呈时间、浓度依赖性。
The alterations of DNA level and cell proliferation dynamics in HL-60 cells induced by RA or DMSO were observed.
以显微分光光度法和流式细胞计观察经维甲酸(RA)或二甲亚砜(DMSO)处理HL-60细胞的DNA含量和细胞增殖的动态变化。
Aim to observe the inhibitory effect of citrus extract Nobiletin on proliferation of leukemia K562 and HL-60 cells.
目的观察柑橘提取物诺必擂停对白血病细胞株k562、H L - 60增殖的抑制作用。
CONCLUSION: Extract sago cycas leaves has remarkable inhibiting effect on proliferation of leukemia K562 and HL-60 cells.
结论:铁树叶提取液对白血病细胞株k562及HL - 60细胞的增殖有明显抑制作用。
Objective to investigate the effect of bortezomib alone and in combination with arsenic trioxide on apoptosis of HL-60 cells.
目的探讨硼替佐米单独或联合了氧化二砷对HL - 60细胞凋亡的影响。
AIM: to explore the effect of alkyl-lysophospholipids (ALP) on the proliferation, apoptosis and differentiation of HL-60 cells.
目的:探讨烷化溶血磷脂(ALP)对HL - 60细胞增殖、凋亡及分化的影响。
Objective To study differential proteomic expression in the differentiation of HL-60 cells induced by diallyl disulfide (DADS).
目的研究二烯丙基二硫(DADS)诱导人髓性白血病HL - 60细胞分化过程中蛋白质组的差异表达。
Results Different concentrations of VEGF markedly inhibited the apoptosis of HL-60 cells and decreased the apoptosis induced by VP16 exposure.
结果VEGF可以明显抑制人急性白血病细胞株hl - 60的凋亡,并且可以对抗VP 16诱导的细胞凋亡效应。
Conclusion 12g5 can change the biological properties of HL-60 cells and inhibit proliferation and survival of leukemia cells at a certain level.
结论12g5可改变HL 60细胞的生物学特性,从而在一定程度上抑制白血病细胞的增殖,影响细胞生存。
Results:After treated with ZTF, typical morphology characters of apoptosis could be found in HL-60 cells through morphologic and agarose gel test;
结果:HL-60细胞经ZTF作用后,形态学和琼脂糖凝胶电泳试验均可观察到明显的细胞凋亡形态;
Results the LIF gene can express in COS-7 cells and the product exhibits following functions on HL-60 cells: inhibiting growth, inducing apoptosis.
结果人LIF基因可在COS - 7细胞中进行有效表达,表达产物对HL - 60白血病细胞具有抑制生长和诱导凋亡的作用。
Methods: in vitro cell culture, MTT titration, NBT reduction and phagocytosis determination were employed to study the effects of JLC on HL-60 cells.
方法:利用体外细胞培养、MTT、NBT染色及吞噬功能测定等方法,观察在不同浓度金龙胶囊作用下人早幼粒白血病细胞系(HL - 60)的细胞形态和功能的变化。
Objective to study the synergy effect of telomerase antisense oligodeoxynucleotide and Liangjin mushroom on apoptosis and telomerase activity of HL-60 cells.
目的研究人类端粒酶反义脱氧核苷酸及其与梁金菇多糖协同作用对HL 6 0细胞凋亡及端粒酶活性的影响。
Results: ICA could inhibit the telomerase activity and induce the differentiation and restrain the proliferation of HL-60 cells. The effect was promoted by ATRA.
结果:ICA可明显抑制端粒酶活性,对白血病细胞均有较明显的诱导分化和抑制增殖作用,且与A TRA合用可产生明显的协同效应。
Objective:To investigate the molecular mechanism of the effect of A3D8, an anti-CD44 monoclonal antibody on proliferation and differentiation of human HL-60 cells.
目的:探讨CD44单克隆抗体A3D8对人急性髓系白血病细胞株HL-60细胞增殖分化影响的分子作用机制。
It was found that these three compounds can induce the differentiation of HL-60 cells in vitro, judged by cell growth inhibition, morphologic observation and NBT reduction ability.
结果表明,在适当的用药浓度下,从细胞生长抑制情况、形态学观察及NBT还原能力测定判断,三种药物对HL - 60细胞有明显的诱导分化作用。
METHODS: The proliferation inhibition effects of LJPS on HL-60 cells was observed by MTT colorimetry. Apoptosis was detected by morphology, flow cytometry and DNA agarose gel electrophoresis.
方法:四氮唑蓝比色法(MTT法)观察梁金菇多糖对HL 6 0细胞的抑制率,应用形态学、流式细胞术、DNA凝胶电泳等方法检测细胞凋亡的发生。
HL 60 and K562 cells showed typical apoptosis features of "ladder" and the sub G1 peak in DNA histogram.
作用HL 60和K562细胞后电泳显示有凋亡细胞特有的“梯状”条带,DNA直方图出现亚g1峰。
Our results showed that the extract or HL 60 cells agglutinated the lymphocytes of mouse spleens.
结果表明,HL-60细胞含有很高的内源性凝集素活性。
Objective: To study the characterization of CK2 from HL 60 cells.
目的:研究人早幼粒白血病HL-60细胞蛋白激酶CK2的性质。
CONCLUSION: ATRA cannot induce HL 60 to achieve terminal differentiation, but the differentiation of HL 60 can be induced by ATRA and the differentiated leukemia cells are easy to apoptosis.
结论:ATRA并不能诱导HL-60细胞完成终端分化,但是该药可以诱导白血病细胞向成熟方向分化,而且已分化的肿瘤细胞于发生凋亡。
CONCLUSION: ATRA cannot induce HL 60 to achieve terminal differentiation, but the differentiation of HL 60 can be induced by ATRA and the differentiated leukemia cells are easy to apoptosis.
结论:ATRA并不能诱导HL-60细胞完成终端分化,但是该药可以诱导白血病细胞向成熟方向分化,而且已分化的肿瘤细胞于发生凋亡。
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