Histone modifications are implicated in influencing gene expression.
蛋白修饰与影响基因表达有关。
We demonstrated a direct role for histone modifications in alternative splicing.
我们证明了组蛋白修饰在选择性剪接中一个直接的作用。
Chromosome banding patterns are correlated with unique patterns of histone modifications.
染色体带型和组蛋白修饰的特有模式相关。
Recent studies have mapped histone modifications across the Saccharomyces cerevisiae genome.
最近的研究对应的组蛋白修饰在酵母基因组中。
Here, we report the patterns derived from the analysis of 39 histone modifications in human CD4 t cells.
这里，我们报告了来自于人类CD 4细胞中39个组蛋白修饰的分析的模式。
We will discuss methods to address these challenges in the context of analyzing histone modifications and DNA methylation data.
我们将在分析组蛋白修饰和DNA甲基化数据的背景下，讨论解决这些挑战的方法。
In this way, histone modifications have the potential to influence many fundamental biological processes, some of which may be epigenetically inherited.
在这种方法中，组蛋白修饰具有影响很多基本生物学过程的潜力，它们中的一些可能是表观上遗传的。
This review focuses on how aberrant covalent histone modifications such as acetylation and methylation may contribute to the development of alimentary canal neoplasms.
主要探讨组蛋白共价修饰中乙酰化和甲基化在消化道肿瘤形成过程中的作用。
More recently a number of laboratories including my own have studied histone modifications and these studies now show that histone H3 is thought to be critical in the response to glucose.
最近许多实验室包括我自己的实验室对组蛋白修饰进行研究，这些研究显示组蛋白h3在对葡萄糖的反应中非常重要。
We found distinctive histone modification signatures that correlate with the splicing outcome in a set of human genes, and modulation of histone modifications causes splice site switching.
我们在一组人类基因中发现了与剪接结果相关的独特的组蛋白修饰特征，及组蛋白导致剪接位点转换的调节。
Histone is the nucleus of chromatin, the covalent modifications in its tails form the histone codes that regulate a number of biological processes.
组蛋白是染色质的核心，其尾部的共价修饰组成组蛋白密码，调节许多生物学事件。
To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants tails.
对于不同状态的染色质，核小体中会组装入相应的组蛋白变体，并且各种组蛋白变体的尾部也能发生多种修饰。
To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants' tails.
对于不同状态的染色质，核小体中会组装入相应的组蛋白变体，并且各种组蛋白变体的尾部也能发生多种修饰。
These modifications serve to alter chromatin structure and accessibility, and to act as docking sites for transcription factors or other histone modifying enzymes.
这些修饰为改变染色质结构和易接近性服务，并作为转录因子或其他组蛋白修饰酶的停靠位点。
The "histone code" is comprised of the covalent modifications of histone tails that function to regulate gene transcription.
“组蛋白密码”是由起调控基因转录功能的组蛋白末端的共价修饰所组成。
These modifications regulate histone-DNA interactions, adding a new dimension to the epigenetic regulation of nucleosome mobility.
这些修饰调控组蛋白- DNA相互作用，为核小体迁移的表观遗传调控添加了新的维度。
These modifications regulate histone-DNA interactions, adding a new dimension to the epigenetic regulation of nucleosome mobility.
这些修饰调控组蛋白- DNA相互作用，为核小体迁移的表观遗传调控添加了新的维度。
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