No aberrant methylation of APC gene was found in the serum samples from healthy control and the patients without gene methylation in tumor tissue.
肿瘤组织未检测到甲基化患者的血清中及健康人血清中均未检测到该基因甲基化变异。
Taken together, these results suggest that glucocorticoid-receptor-gene methylation happens in the fetus in response to a mother's stress, and persists into adolescence.
总体看来，这些结论表明胎儿糖皮质激素受体基因的甲基化是由于母亲压力过大引起的，并且其影响将会持续到青春期。
In 40 research patients in the UK that are participating in an ongoing study that has documented many aspects of their lives, researchers looked at differences in gene methylation.
英国的40名患者参加了一项持续研究，在这项研究中，他们人生中的很多方面都被记录下来，研究者们观察了他们基因甲基化的差异。
He didn't speculate as to which is the more likely culprit, but said that many things, such as gene mutations, could cause defects in methylation that might result in infertility.
至于哪个更可能是原因他并没能做出预测，但是他说许多东西如基因突变也能导致甲基化的缺陷，这也可能导致不育。
If you look in the normal population and ask what fraction of people have [a defect in methylation in the gene encoding insulin-like growth factor 2] it's about 5 percent.
如果你观察普通人群，调查多少比例的人有[胰岛素类生长因子2基因编码甲基化的缺陷]，大概是百分之5。
But in the daughters of obese fathers, the level of methylation of this gene was around 25% of the level seen in the control daughters.
但在父亲肥胖的雌鼠身上，该基因的甲基化水平仅占对照组雌鼠的25%左右。
The plants were derived from two Arabidopsis parents with essentially identical genomes, but with one having a mutated DDM1 DNA methylation gene.
这些植株源自两棵基因几乎相同的拟南芥，但其中一棵含有突变的DDM1甲基化DNA。
Their team examined the methylation of the glucocorticoid-receptor gene in a group of children ranging in age from ten to 19 years, and in those children's mothers.
他们的团队对一组10到19岁的儿童进行了糖皮质激素受体基因甲基化的检测，并对他们的妈妈做了同样的检测。
When a methyl group attaches to a specific spot on a gene - a process called DNA methylation.
甲基附加到基因上某个特殊点的过程，称为DNA甲基化。
Rats that had experienced little maternal care showed high levels of methylation and low levels of acetylation of the glucocorticoid-receptor gene and its neighbouring proteins.
是否应该是 缺少关爱的老鼠糖皮质激素受体基因和 基因周边的蛋白质表现出高水平的甲基化及较低水平的乙酰化。 另，acetylation 是否应该是乙醇化？
Epigenetics is a type of gene regulation that can be passed from a cell to its daughters. The most common mechanism is methylation.
外因遗传是一种可以传给下一代细胞的基因调控过程，最常见的方式是通过甲基化作用来完成，该作用可以让甲基（由一个碳原子和三个氢原子组成）附着于腺嘌呤或胞嘧啶上。
By contrast, L-methionine increased the level of methylation and thus reduced the expression of the gene in animals with loving mothers, and led to fear, anxiety and a heightened response to stress.
与之相反，L -甲硫氨酸增加了甲基化水平，从而减弱了正常老鼠中糖皮质激素受体基因的表达，导致了恐惧、焦虑和对压力的强烈反应。
Discussing the relations of DNA methylation and gene transcriptional silencing takes on important significances for the study of many human diseases.
探讨DNA甲基化与基因转录抑制之间的关系，对许多人类疾病的研究具有重要意义。
They then measured methylation levels in the RASSF1A gene in epithelial cells that lined the ducts.
然后测定了这些导管上皮细胞RASSF1A基因的甲基化程度。
DNA methylation in the promoter regions is a powerful mechanism for the suppression of gene activity.
在启动子区域的DNA甲基化是抑制基因活性的一种重要机制。
DNA methylation plays an important role in gene regulation and animal development.
DNA甲基化在基因调节和动物发育中起着重要作用。
The role of histone lysine methylation in the gene expression regulation has turned into the hotspot of epigenetics.
组蛋白赖氨酸甲基化在基因表达调控中的作用已成为表观遗传学研究的热点。
Conclusion Abnormal methylation of TPEF gene is a frequent event and may become a promising diagnostic marker for early detecting colorectal carcinoma.
结论大肠癌患者TPEF基因甲基化为一频繁发生事件，可望成为大肠癌早期诊断的一个标志物。
The methylation of histone H3-K27 was proved to be linked to several silencing phenomena including homeotic-gene silencing, X inactivation and genomic imprinting.
组蛋白H3第27位赖氨酸的甲基化与同源盒基因沉默、X染色体失活、基因印记等基因沉默现象有关；
This phenomenon is mostly seen in imprinted genes and X-chromosome inactivation where DNA methylation of promoter regions leads to repression of gene expression.
这种现象主要在印迹基因和X染色体失活区域看到，这些区域中的启动子区的DNA甲基化导致了基因表达的抑制。
DNA methylation, which has been widely considered as the most important mechanism for normal and pathological gene expression, has been listed among the hotspots of molecular biology research.
DNA甲基化已成为阐明正常和病理基因表达现象的重要机制，因而已成为当前分子生物学的研究热点之一。
To evaluate the possibility of methylation analysis of secreted frizzled-related protein gene 2(SFRP2)in feces for screening early colorectal cancer (CRC).
目的探讨人粪便中分泌型卷曲相关蛋白2（SFRP2）基因甲基化分析用于结直肠癌（CRC）早期诊断的可行性。
The methylation beautification is the vertebrate DNA only nature beautification way, the animal genome team methylation and the gene expression close related.
甲基化修饰是脊椎动物DNA唯一的自然修饰方式，动物基因组甲基化与基因表达密切相关。
Aim: to detect the methylation at the promoter P3 of human insulin-like growth factor II (IGF-II) gene in hepatocellular carcinoma.
目的：建立检测肝癌胰岛素样生长因子ii (IGF - II)基因启动子p3甲基化状态的方法。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
DNA甲基化由DNA甲基转移酶催化，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。
Objective to investigate methylation of BLU gene in hepatocellular carcinoma.
目的了解肝细胞癌中blu基因的甲基化状态及临床意义。
Cancer cells have abnormal levels of methylation, which turns the gene switch off halting the assembly line of critical proteins found in normal cells.
癌细胞甲基化水平的异常导致基因开关关闭，使得正常细胞关键蛋白的装配线出现缺陷。
Epigenetic processes, such as DNA methylation, are known to regulate tissue specific gene expression.
已知表观遗传过程，例如DNA甲基化调控组织特异基因表达。
Epigenetic processes, such as DNA methylation, are known to regulate tissue specific gene expression.
已知表观遗传过程，例如DNA甲基化调控组织特异基因表达。
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