Studies of animals, for example, have shown that when a rat experiences stress during pregnancy, it can cause epigenetic changes in a fetus that lead to behavioral problems as the rodent grows up.
例如,对动物的研究表明,老鼠在怀孕期间经历压力会导致胎儿表观遗传发生变化,进而导致啮齿动物在成长过程中出现行为问题。
When animals are cloned, epigenetic changes can occur.
克隆动物后,表观遗传的变化就会发生。
Epigenetic changes represent a biological response to an environmental stressor.
外基因改变是受环境压力后的生物反应。
These techniques are revealing in great details massive epigenetic changes in cancer.
这些技术正极详细地揭示癌症中大量的表观变化。
Aberrant methylation of DNA has been recognized as common epigenetic changes in human cancer.
DNA异常甲基化是肿瘤常见的表观遗传学改变。
Therapeutically, it may mean that preventing oxidative stress may stop epigenetic changes in DNA.
在治疗学上它意味着预防氧化应激可以中止DNA的表观遗传学改变。
The first direct evidence has been found linking smoking to epigenetic changes in genes that help fight cancer.
科学家首次发现了吸烟与抗癌基因表观变化存在关联的直接证据。
Improving technologies are now providing a broader look at the epigenetic changes linked to environment and behavior.
日新月异的科技使得我们可以用更广阔的视野看待与环境和行为相联系的表观遗传变化。
But it's hard to tell in most natural populations whether inheritance is due to DNA sequence variation or epigenetic changes.
但在自然界大多数种群中,很难判断遗传是否源于DNA序列改变或者表观基因变异。
The tumor suppressor gene FHIT is inactivated by genetic and epigenetic changes in the majority of common human cancers.
多数常见癌症中,肿瘤抑制基因FHIT的表达因受遗传或表观遗传因素的作用而受到抑制。
Epigenetic changes are heritable changes to the regulation of a cell's genes, caused by extra molecules being attached to those genes.
表观遗传变异是由附属于基因的其他分子作用引起基因表达改变的可遗传的变异。
It may be that epigenetic changes could be reinforced by mutations in the DNA, making them stable and heritable in the conventional way.
也许表观基因变异会因DNA突变而得到强化,且由此变得稳定并以常规方式遗传下去。
The result indicated that speciation ofallopolyploid wheat induced rapid and extensive genetic and epigenetic changes in thegenome.
结果表明,小麦异源六倍体物种形成诱发迅速且广泛的基因组遗传变异和表观遗传变异。
The most striking finding was the presence of epigenetic changes meaning that the DNA is altered and this alteration lasts for long periods.
最引人注目的发现是意味着DNA改变的表观遗传学变化的存在,而且这种改变会持续很长一段时间。
Andrew Hudson at the University of Edinburgh says there is a clear implication that "DNA methylation and epigenetic changes are important in evolution."
爱丁堡大学的AndrewHudson表示,这明显意味着“DNA甲基化和表观基因变异在进化中是非常重要的”。
If Chong's group can confirm that fetal alcohol syndrome causes epigenetic changes in humans too, it might allow the syndrome to be spotted earlier on in life.
如果Chong的研究小组能够证明,胎儿酒精综合征导致人类出现表观遗传变异,也许我们在生命形成的更早阶段就可以发现它。
Many researchers say these so-called epigenetic changes are as important as genomic variation to controlling cell function and, ultimately, an individual's health.
许多研究者认为这种所谓的次生变化在控制细胞功能及最终控制个体健康方面与基因组的变化同样重要。
This suggests that if women drink too much in pregnancy, epigenetic changes may cause some of the permanent symptoms seen in fetal alcohol syndrome in their children.
这表明,妇女如果在孕期饮酒过多,表观遗传变异可能会导致他们的子女出现胎儿酒精综合征中的一些固定症状。
Teratocarcinomas can arise through purely epigenetic changes and represent an extreme case in which the transformed phenotype can be abrogated under appropriate conditions.
畸胎瘤可能仅仅因为后生改变而出现,这代表一个极端的例子,其转化表型可以在适当条件下被废除。
Crucially, these well-adjusted rats then gave their own babies the same type of care-in effect, transmitting the behaviour from mother to daughter by inducing similar epigenetic changes.
至关重要的是,这些适应力强的老鼠也给它们自己的下一代同样的关怀,而实际上这正是因为诱导发生了相似的表现遗传学变化,使得这种行为代代相传。
The EWG added that exposure can also cause epigenetic changes, meaning alterations in the way genes switch off and on and genetic changes that can be passed on to the next generation.
EWG补充说暴露在PBA下还会导致遗传性变异,意味则各种基因的变异能够遗传到一下代身上。
Environmentally triggered alterations in genes - known as epigenetic changes - can affect when a gene is activated, how robustly it is turned on and how it interacts with neighboring genes.
环境所引发的基因变异被称为“表观遗传变化”,它可能会影响基因被激活的时间、被激活的程度以及它如何与邻近基因相互配合。
International Digest: Most features of the cancer cell can be explained by genetic or epigenetic changes. Can you talk about the latest progress in terms of hepatocellular carcinoma (HCC)?
国际肝病:癌症细胞大多数特征可以通过遗传或表观遗传的改变来解释。您能谈谈关于肝细胞癌(HCC)最新的进展吗?
But because the DNA code itself remained unchanged, Morris's team suggest that the changes in gene expression are epigenetic.
但由于DNA密码本身并无变化,莫里斯的团队认为这些基因表达的调整是表观的。
Methylation is an epigenetic modification to one's DNA that changes a gene's activity, generally reducing that activity within the genome.
甲基化作用是对DNA的后天修改,并改变基因活动,通常是在基因组内减少这个活动。
Such "epigenetic" chemical changes don't change the genetic code, but can mean that a gene's function is increased or decreased, or switched on or off.
这种“表现”化学变化并不改变遗传密码,但可能意味着一个基因的功能被加强抑或减弱、被打开还是被关闭。
Epigenetic is the latest biological science in recent years, which mainly researches gene function reversible and heritable variation without DNA sequence changes.
表观遗传学是近年来新兴起的生物学学科,主要研究在没有DNA序列改变情况下基因功能可逆的、可遗传的变异。
EpigeneticsStudies in animals have shown that changes in diet can alter the function of genes - known as epigenetic change.
一项针对动物的研究发现,饮食的变化能改变基因的功能——这种变化被称为表观遗传变化。
Epigenetic mutations confer heritable changes in gene expression that are not due to changes in the underlying sequence of the DNA.
表观遗传突变是指没有引起DNA序列变化的可遗传的基因表达改变。
Epigenetic mutations confer heritable changes in gene expression that are not due to changes in the underlying sequence of the DNA.
表观遗传突变是指没有引起DNA序列变化的可遗传的基因表达改变。
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