Objective: To promote the study of drug metabolic enzymes in clinical practice.
目的:为了促进药物代谢酶在临床上的深入研究。
Intestinal drug transporters, hepatic drug metabolic enzymes and the kidney play a very important role in the process of ADME.
肠道转运体、肝脏药物代谢酶及肾脏在药物adme过程中发挥着重要作用。
Conclusion: the study of drug metabolic enzymes will help to provide safe, rational and effective prescriptions and to decrease the adverse drug reactions.
结论:药物代谢酶的认识和研究有助于临床合理用药和减少药物不良反应。
Polymorphisms exist in human genomic DNA. And some polymorphisms such as metabolic enzymes, drug receptors, and some other genes correlated with diseases may affect the drug responsiveness.
人群中DNA存在多态性,与药物反应相关的基因多态性可能产生药物效应的个体差异,例如药物代谢酶、药物作用受体以及其它一些与疾病相关基因等。
Polymorphisms exist in human genomic DNA. And some polymorphisms such as metabolic enzymes, drug receptors, and some other genes correlated with diseases may affect the drug responsiveness.
人群中DNA存在多态性,与药物反应相关的基因多态性可能产生药物效应的个体差异,例如药物代谢酶、药物作用受体以及其它一些与疾病相关基因等。
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